In recent years, researchers have demonstrated that estrogen and its receptors, aside from
their role in regulating several biological functions, contribute to the development and …

Epidemiological studies show that oestrogen reduces the risk of colorectal cancer in
postmenopausal women and ERβ (oestrogen receptor β)-selective ligands have been …

Estrogen has a pivotal role in many biological functions in both reproductive and non-
reproductive organs, mediating actions through its receptors, estrogen receptor?(ER?) and …

Crohn disease (CD) and ulcerative colitis (UC) are chronic forms of inflammatory bowel
disease (IBD) whose pathogenesis is only poorly understood. Estrogens have a complex …

Crohn's disease (CD) and ulcerative colitis (UC), collectively known as inflammatory bowel
diseases, are archetypical inflammatory disorders of the gastrointestinal tract with rising …

Estrogen receptor‐beta (ERβ) has been suggested to exert anti‐inflammatory and anti‐
tumorigenic effects in the colon, providing a translational potential to prevent and/or treat …

BACKGROUND & AIMS: Estrogen has been proposed to modulate gut inflammation through
an effect on estrogen receptors found on gastrointestinal epithelial and immune cells. The …

Ulcerative colitis (UC) is a condition at increased risk for colorectal carcinoma (CRC)
development. Nowadays, screening and follow-up programs are routinely performed …

Males are at greater risk than females for developing ulcerative colitis (UC) and
experiencing worse clinical disease 1–3; the molecular basis for this sex bias remains …

Hormones have become a useful therapeutic aspect of clinical endocrinology but how to use
them to optimize the health benefits and avoid adverse effects is a major challenge …