Obesity and the risk of gastrointestinal cancers

J Karczewski, B Begier-Krasińska, R Staszewski… - Digestive diseases and …, 2019 - Springer
Obesity is a risk factor for all major gastrointestinal cancers. With the rapid increase in the
prevalence of obesity worldwide, this link could lead to an elevated burden of cancers of the …

Adiposity and gastrointestinal cancers: epidemiology, mechanisms and future directions

N Murphy, M Jenab, MJ Gunter - Nature Reviews Gastroenterology & …, 2018 - nature.com
Excess adiposity is a risk factor for several cancers of the gastrointestinal system, specifically
oesophageal adenocarcinoma and colorectal, small intestine, pancreatic, liver, gallbladder …

Mechanisms behind the link between obesity and gastrointestinal cancers

H Tilg, AR Moschen - Best practice & research Clinical gastroenterology, 2014 - Elsevier
Obesity and obesity-related disorders such as non-alcoholic fatty liver disease (NAFLD),
metabolic syndrome and type 2 diabetes exhibit an increased risk of developing various …

Obesity-related gut hormones and cancer: Novel insight into the pathophysiology

MA Guzzardi, G Pugliese, F Bottiglieri… - International Journal of …, 2021 - nature.com
The number of cancers attributed to obesity is increasing over time. The mechanisms
classically implicated in cancer pathogenesis and progression in patients with obesity …

Obesity and cancer

H Ungefroren, F Gieseler, S Fliedner… - … molecular biology and …, 2015 - degruyter.com
The incidence of obesity in the Western world has increased dramatically during the recent
decades. Epidemiological data suggest that obesity is associated with an increased risk of …

From obesity to cancer: a review on proposed mechanisms

Z Tahergorabi, M Khazaei, M Moodi… - Cell biochemistry and …, 2016 - Wiley Online Library
Nowadays, obesity is considered as a serious and growing global health problem. It is
documented that the overweight and obesity are major risk factors for a series of …

Physiological and environmental factors affecting cancer risk and prognosis in obesity

PFS Etet, L Vecchio, AHN Kamdje, PN Mimche… - Seminars in Cancer …, 2023 - Elsevier
Obesity results from a chronic excessive accumulation of adipose tissue due to a long-term
imbalance between energy intake and expenditure. Available epidemiological and clinical …

Obesity and gastrointestinal cancer: the interrelationship of adipose and tumour microenvironments

J O'Sullivan, J Lysaght, CL Donohoe… - Nature reviews …, 2018 - nature.com
Increasing recognition of an association between obesity and many cancer types exists, but
how the myriad of local and systemic effects of obesity affect key cellular and non-cellular …

The mechanisms linking obesity to colon cancer: An overview

A Tarasiuk, P Mosińska, J Fichna - Obesity research & clinical practice, 2018 - Elsevier
Obesity, characterised as a chronic low-grade inflammation is a crucial risk factor for colon
cancer. The expansion of the adipose tissue is related to elevated triglyceride and low …

Mechanisms linking excess adiposity and carcinogenesis promotion

AI Pérez-Hernández, V Catalán… - Frontiers in …, 2014 - frontiersin.org
Obesity constitutes one of the most important metabolic diseases being associated to insulin
resistance development and increased cardiovascular risk. Association between obesity …