Correlation between HGF/c-Met and Notch1 signaling pathways in human gastric cancer cells

KH Huang, I Sung, WL Fang, CW Chi… - Oncology …, 2018 - spandidos-publications.com
In recent decades, research concerning gastric carcinogenesis has rapidly progressed. It is
evident that hepatocyte growth factor (HGF) is clinically related to gastric cancer progression …

The activated Notch1 signal pathway is associated with gastric cancer progression through cyclooxygenase-2

TS Yeh, CW Wu, KW Hsu, WJ Liao, MC Yang, AFY Li… - Cancer research, 2009 - AACR
Gastric carcinoma is one of the most common cancers and lethal malignancies worldwide.
Thus far, the regulatory mechanisms of its aggressiveness are still poorly understood. To …

[HTML][HTML] Role of Notch signaling pathway in gastric cancer: a meta-analysis of the literature

X Du, Z Cheng, YH Wang, ZH Guo… - World Journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To perform a meta-analysis to quantitatively summarize the evidence for the
association between the Notch signaling pathway and gastric cancer (GC). METHODS: An …

Notch2‐induced COX‐2 expression enhancing gastric cancer progression

YC Tseng, YH Tsai, MJ Tseng, KW Hsu… - Molecular …, 2012 - Wiley Online Library
Gastric carcinoma is one of the most common and mortal types of malignancy worldwide. To
date, the mechanisms controlling its aggressiveness are not yet fully understood. Notch …

[HTML][HTML] Elevated expression of NOTCH1 associates with lymph node metastasis of gastric cancer and knock-down of NOTCH1 attenuates tumor cell progression

B Huang, G Jin, C Qu, H Ma, C Ding… - … Medical Journal of …, 2019 - ncbi.nlm.nih.gov
Elevated Expression of NOTCH1 Associates with Lymph Node Metastasis of Gastric Cancer
and Knock-Down of NOTCH1 Attenuates Tumor Cell Progression - PMC Back to Top Skip to …

Elevated Notch-1 expression promotes the lymph node metastasis of gastric cancer and the Notch-1-PTEN-ERK1/2 signalling axis promotes the progression of gastric …

H Ma, N Li, Z Mo - Cytokine, 2022 - Elsevier
Background Gastric cancer (GC) is one of the most common malignant tumours and has a
high fatality rate worldwide. This study investigated the role of the Notch-1 signalling …

Downregulation of Notch1 inhibits the invasion and metastasis of human gastric cancer cells SGC7901 and MKN74 in vitro through PTEN activation and …

XS Zhang, YH Hu, HY Gao… - Molecular Medicine …, 2017 - spandidos-publications.com
Migration and invasion are both vital causes of mortality in patients with gastric cancer.
Therefore, the inhibition of these tumour cell processes is of great importance in gastric …

Notch4 promotes gastric cancer growth through activation of Wnt1/β-catenin signaling

C Qian, F Liu, B Ye, X Zhang, Y Liang, J Yao - Molecular and cellular …, 2015 - Springer
Gastric cancer (GC) is one of the most common cancers and lethal malignancies in the
world. Discovering novel biomarkers that correlate with GC may provide opportunities to …

[HTML][HTML] Notch and mTOR signaling pathways promote human gastric cancer cell proliferation

ES Hibdon, N Razumilava, TM Keeley, G Wong… - Neoplasia, 2019 - Elsevier
Notch pathway signaling is known to promote gastric stem cell proliferation, and constitutive
pathway activation induces gastric tumors via mTORC1 activation in mouse genetic models …

The function of Notch1 intracellular domain in the differentiation of gastric cancer

S Hu, Q Chen, T Lin, W Hong, W Wu… - Oncology …, 2018 - spandidos-publications.com
Due to the complex function of the Notch signal pathway in gastric cancer (GC), the
association between Notch homolog 1 (Notch1) intracellular domain (NICD) and …