Natural and synthetic flavonoids: structure–activity relationship and chemotherapeutic potential for the treatment of leukemia

JC Menezes, B Orlikova, F Morceau… - Critical reviews in food …, 2016 - Taylor & Francis
Flavonoids and their derivatives are polyphenolic secondary metabolites with an extensive
spectrum of pharmacological activities, including antioxidants, antitumor, anti-inflammatory …

[HTML][HTML] Chemopreventive and anticancer activity of flavonoids and its possibility for clinical use by combining with conventional chemotherapeutic agents

H Kikuchi, B Yuan, X Hu, M Okazaki - American journal of cancer …, 2019 - ncbi.nlm.nih.gov
Cancer is a diverse class of diseases characterized by uncontrolled cell growth with the
potential to invade and spread to other parts of the body, and continues to be one of the …

Established human cell lines as models to study anti-leukemic effects of flavonoids

K Sak, H Everaus - Current genomics, 2017 - ingentaconnect.com
Despite the extensive work on pathological mechanisms and some recent advances in the
treatment of different hematological malignancies, leukemia continues to present a …

Leukemia therapy by flavonoids: Future and involved mechanisms

R Saraei, F Marofi, A Naimi, M Talebi… - Journal of cellular …, 2019 - Wiley Online Library
Flavonoids are a varied family of phytonutrients (plant chemicals) usually are detected in
fruits and vegetables. In this big family, there exist more than 10,000 members that is …

Flavonoids as anticancer agents

DM Kopustinskiene, V Jakstas, A Savickas… - Nutrients, 2020 - mdpi.com
Flavonoids are polyphenolic compounds subdivided into 6 groups: isoflavonoids,
flavanones, flavanols, flavonols, flavones and anthocyanidins found in a variety of plants …

[HTML][HTML] Flavonoids: A versatile source of anticancer drugs

MK Chahar, N Sharma, MP Dobhal… - Pharmacognosy …, 2011 - ncbi.nlm.nih.gov
An exponential increase in the number of studies investigating how different components of
the diet interact at the molecular and cellular level to determine the fate of a cell has been …

Flavonoids as anticancer agents: structure-activity relationship study

M Lopez-Lazaro - Current Medicinal Chemistry-Anti-Cancer …, 2002 - ingentaconnect.com
The protection against some forms of cancer provided by many common foods has been
observed in multiple epidemiological studies. Non-nutritive dietary compounds, such as …

The hallmarks of flavonoids in cancer

LGS Ponte, ICB Pavan, MCS Mancini, LGS da Silva… - Molecules, 2021 - mdpi.com
Flavonoids represent an important group of bioactive compounds derived from plant-based
foods and beverages with known biological activity in cells. From the modulation of …

Role of polyphenols and flavonoids as anti-cancer drug candidates: A review

MM Hegde, K Lakshman - Pharmacognosy Research, 2023 - phcogres.com
Natural drug-based chemotherapeutic have advanced at an unprecedented rate over the
past decade. Owing to protective roles in vegetation, and exceptional antioxidant qualities …

Role of plant-derived flavonoids in cancer treatment

P Tiwari, KP Mishra - Nutrition and Cancer, 2023 - Taylor & Francis
Flavonoids are polyphenolic phytochemicals, which occur naturally in plants and possess
both anti-oxidant and pro-oxidant properties. Flavonoids are gaining increasing popularity in …