Research into TBI biomarkers has accelerated rapidly in the past decade owing to the
heterogeneous nature of TBI pathologies and management, which pose challenges to TBI …

Multi-modal biomarkers (eg, imaging, blood-based, physiological) of unique traumatic brain
injury (TBI) endophenotypes are necessary to guide the development of personalized and …

Traumatic brain injuries (TBIs) are caused by a hit to the head or a sudden acceleration/
deceleration movement of the head. Mild TBIs (mTBIs) and concussions are difficult to …

Blood-based protein biomarkers have revolutionized several fields of medicine by enabling
molecular level diagnosis, as well as monitoring disease progression and treatment efficacy …

Background Several studies have reported an association between serum biomarker values
and functional outcome following traumatic brain injury. We aimed to examine the …

Accurate diagnosis for mild traumatic brain injury (mTBI) remains challenging, as prognosis
and return-to-play/work decisions are based largely on patient reports. Numerous …

Background: Advances in the understanding of human biochemistry and physiology have
provided insight into new pathways by which we can understand traumatic brain injury (TBI) …

The aim of the study was to examine the ability of eight protein biomarkers and their
combinations in discriminating computed tomography (CT)-negative and CT-positive …

Brain-enriched protein biomarkers of tissue fate are being introduced clinically to aid in
traumatic brain injury (TBI) management. The aim of this study was to determine how …

Background The use of blood biomarkers after mild traumatic brain injury (mTBI) has been
widely studied. We have identified eight unresolved issues related to the use of five …