Importance In 2018, the combination of glial fibrillary acidic protein (GFAP) and ubiquitin C-
terminal hydrolase (UCH-L1) levels became the first US Food and Drug Administration …

Purpose This review summarizes protein biomarkers in mild and severe traumatic brain
injury in adults and children and presents a strategy for conducting rationally designed …

Emerging evidence suggests that biofluid-based biomarkers have diagnostic and prognostic
potential in traumatic brain injuries (TBI). However, owing to the lack of a conceptual …

Objective This study assessed whether early levels of biomarkers measured in CSF within
24-h of severe TBI would improve the clinical prediction of 6-months mortality. Methods This …

Abstract VISSER, K., M. Koggel, J. Blaauw, HJvd Horn, B. Jacobs, and Jvd Naalt. Blood
based biomarkers of inflammation in mild traumatic brain injury: A systematic review …

There is substantial interest in the potential for traumatic brain injury to result in progressive
neurological deterioration. While blood biomarkers such as glial fibrillary acid protein …

Traumatic brain injury (TBI) is a leading cause of morbidity and mortality in adults and
children. Predicting outcome after TBI is difficult, but it is important for acute management …

Recent contributions to the body of knowledge on traumatic brain injury (TBI) favor the view
that multimodal neuroimaging using structural and functional magnetic resonance imaging …

Background The prognostic value of glial fibrillary acidic protein (GFAP) and ubiquitin C-
terminal hydrolase L1 (UCH-L1) as day-of-injury predictors of functional outcome after …

Although mild traumatic brain injury (mTBI), or concussion, is not typically associated with
abnormalities on computed tomography (CT), it nevertheless causes persistent cognitive …