G protein-coupled receptors (GPCRs) not only exist as monomers but also as homomers
and heteromers in which allosteric receptor-receptor interactions take place, modulating the …

Although the G protein-coupled receptor (GPCR) oligomerization has been questioned
during the last decade, under some premises the existence of a supramolecular …

The functional importance of G protein-coupled receptor (GPCR) oligomerization remains
controversial. Although obligate dimers of class C GPCRs are well accepted, the …

Through an assembly of interacting GPCRs, heterodimers and high-order heteromers
(termed receptor mosaics) are formed and lead to changes in the agonist recognition …

G protein-coupled receptor (GPCR)-mediated signal transduction has been studied for more
than a century. Despite the intense focus on this class of proteins, a molecular …

The idea that G protein‐coupled receptors (GPCRs) may undergo homo‐or hetero‐
oligomerization, although highly controversial up to a few years ago, has recently gained …

The discovery that receptors from all families can establish allosteric receptor–receptor
interactions and variably associate to form receptor complexes operating as integrative input …

Allosteric regulation of ligand binding is a well-established mechanism regulating the
function of G protein-coupled receptors (GPCR). Allosteric modulators have been …

G-protein-coupled receptors (GPCRs) are a widespread family of transmembrane receptors
with different physiologically relevant functions. Alterations in the structure and function of …

It is becoming accepted that G‐protein‐coupled receptors (GPCRs) arrange in the neuronal
membrane into homo‐and hetero‐oligomers and, therefore, these complexes mediate …