[HTML][HTML] Mechanisms of CD8+ T-cell failure in chronic hepatitis E virus infection
J Kemming, S Gundlach, M Panning, D Huzly… - Journal of …, 2022 - Elsevier
Background & Aims In immunosuppressed patients, persistent HEV infection is common and
may lead to cirrhosis and liver failure. HEV clearance depends on an effective virus-specific …
may lead to cirrhosis and liver failure. HEV clearance depends on an effective virus-specific …
Hepatitis E virus (HEV)‐specific T‐cell responses are associated with control of HEV infection
PV Suneetha, S Pischke, V Schlaphoff… - …, 2012 - Wiley Online Library
Hepatitis E virus (HEV) infection is usually self‐limited but may lead to acute hepatitis and
rarely to fulminant hepatic failure. Persistent HEV infections have recently been described in …
rarely to fulminant hepatic failure. Persistent HEV infections have recently been described in …
[HTML][HTML] Hepatitis E virus infection—immune responses to an underestimated global threat
P Kupke, JM Werner - Cells, 2021 - mdpi.com
Infection with the hepatitis E virus (HEV) is one of the main ubiquitous causes for developing
an acute hepatitis. Moreover, chronification plays a predominant role in …
an acute hepatitis. Moreover, chronification plays a predominant role in …
Resolution of hepatitis E virus infection in CD8+ T cell-depleted rhesus macaques
Background & Aims HEV is a significant cause of acute hepatitis globally. Some genotypes
establish persistent infection when immunity is impaired. Adaptive immune mechanisms that …
establish persistent infection when immunity is impaired. Adaptive immune mechanisms that …
Defining virus-specific CD8+ TCR repertoires for therapeutic regeneration of T cells against chronic hepatitis E
CF Soon, P Behrendt, D Todt, MP Manns… - Journal of …, 2019 - Elsevier
Background & Aims Immunosuppressed patients with chronic hepatitis E virus infection
(cHEV), who are ineligible or have failed current treatment with off-label ribavirin, are a …
(cHEV), who are ineligible or have failed current treatment with off-label ribavirin, are a …
[PDF][PDF] Characterization of the specificity, functionality, and durability of host T‐cell responses against the full‐length hepatitis E virus
A Brown, JS Halliday, L Swadling, RG Madden… - …, 2016 - Wiley Online Library
The interplay between host antiviral immunity and immunopathology during hepatitis E virus
(HEV) infection determines important clinical outcomes. We characterized the specificity …
(HEV) infection determines important clinical outcomes. We characterized the specificity …
Immunopathogenesis of hepatitis E virus infection
H Wedemeyer, J Rybczynska, S Pischke… - Seminars in liver …, 2013 - thieme-connect.com
The course of hepatitis E virus infection (HEV) can vary substantially between different
individuals. Although most infections take a clinically silent asymptomatic course, a few …
individuals. Although most infections take a clinically silent asymptomatic course, a few …
[HTML][HTML] Case report: chronic hepatitis E virus infection in an individual without evidence for immune deficiency
D Ying, W Niu, Y Chen, Y Wang, W Tian… - Frontiers in …, 2023 - frontiersin.org
Chronic hepatitis E virus (HEV) infection occurs mainly in immunosuppressed populations.
We describe an investigation of chronic HEV infection of genotype 3a in an individual …
We describe an investigation of chronic HEV infection of genotype 3a in an individual …
Cross‐genotype‐specific T‐cell responses in acute hepatitis E virus (HEV) infection
A Gisa, PV Suneetha, P Behrendt… - Journal of Viral …, 2016 - Wiley Online Library
Hepatitis E is an inflammatory liver disease caused by infection with the hepatitis E virus
(HEV). In tropical regions, HEV is highly endemic and predominantly mediated by HEV …
(HEV). In tropical regions, HEV is highly endemic and predominantly mediated by HEV …
Conventional and innate lymphocytes response at the acute phase of HEV infection in transplanted patients
F Abravanel, H Barragué, G Dörr, K Sauné, JM Péron… - Journal of Infection, 2016 - Elsevier
Objectives The hepatitis E virus (HEV) causes usually benign and spontaneously resolving
acute hepatitis in immunocompetent individuals. In immunocompromised patients with a …
acute hepatitis in immunocompetent individuals. In immunocompromised patients with a …