There is a complex interaction between the brain and the cerebral vasculature to meet the
metabolic demands of the brain for proper function. Preservation of cerebrovascular function …

Efficient blood supply to the brain is of paramount importance to its normal functioning and
improper blood flow can result in potentially devastating neurological consequences …

To a great extent, cognitive health depends on cerebrovascular health and a deeper
understanding of the subtle interactions between cerebrovascular function and cognition is …

The relationship between cerebral hemodynamics and cognitive performance has
increasingly become recognized as a major challenge in clinical practice for older adults …

The effects of the renin–angiotensin system (RAS) surpass the renal and cardiovascular
systems to encompass other body tissues and organs, including the brain. Angiotensin II …

Background and Purpose—This scientific statement provides an overview of the evidence
on vascular contributions to cognitive impairment and dementia. Vascular contributions to …

Vascular contributions to cognitive impairment and dementia (VCID) is one of the leading
causes of dementia along with Alzheimer's disease (AD) and, importantly, VCID often …

Considerable information is currently available from neuroimaging, pathological, and
population-based prospective studies showing that vascular risk factors are independently …

Increasing evidence from epidemiological, clinical and experimental studies indicate that
age-related cerebromicrovascular dysfunction and microcirculatory damage play critical …

Executive dysfunction is the most important predictor for loss of independence in dementia.
As executive function involves the coordination of distributed cerebral functions, executive …