Inhalation of molecular hydrogen (H2) gas ameliorates oxidative stress-induced acute
injuries in the brain. Consumption of water nearly saturated with H2 also prevents chronic …

Background/Aims: Hydrogen selectively neutralizes reactive oxygen species (ROS) and
ameliorates various ROS-induced injuries. Spinal cord injury (SCI) is a serious injury to the …

Molecular hydrogen (H2) was believed to be an inert and nonfunctional molecule in
mammalian cells; however, we overturned the concept by reporting the therapeutic effects of …

Neonatal hypoxic‐ischemic encephalopathy (HIE) is a leading cause of death in neonates
with no effective treatments. Recent advancements in hydrogen (H2) gas offer a promising …

Background & Aims: Deep hypothermic circulatory arrest (DHCA) is a cerebral protection
technique that has been used in the operations involving the aortic arch and brain aneurysm …

Traumatic brain injury (TBI) is a leading cause of mortality and disability among the young
population. It has been shown that hydrogen gas (H2) exerts a therapeutic antioxidant …

Hydrogen sulfide (H2S), an endogenous gaseous mediator, has been shown to exert
protective effects against damage to different organs in the human body caused by various …

Obstructive sleep apnea (OSA) is a very common breathing and sleep disorder
characterized by intermittent hypoxia (IH), which is often associated with behavioral and …

Oxidative stress (OS) and neuroinflammatory stress affect many neurological disorders.
Despite the clinical significance of oxidative damage in neurological disorders, still, no …

Hyperbaric oxygen (HBO) therapy through breathing oxygen at the pressure of above 1
atmosphere absolute (ATA) is useful for varieties of clinical conditions, especially hypoxic …