The 'in's and out's' of descending pain modulation from the rostral ventromedial medulla
CC De Preter, MM Heinricher - Trends in Neurosciences, 2024 - cell.com
… -pain modulating circuit controls the experience of pain by … This circuit’s key output node,
the rostral ventromedial medulla … respectively suppress or facilitate pain-related sensory pro…
the rostral ventromedial medulla … respectively suppress or facilitate pain-related sensory pro…
Pain modulation from the brain during diabetic neuropathy: uncovering the role of the rostroventromedial medulla
… rostroventromedial medulla (RVM) is a key pain control center involved in descending pain
modulation … mechanisms that mediate nociceptive modulation from the RVM during diabetes …
modulation … mechanisms that mediate nociceptive modulation from the RVM during diabetes …
Inputs to the locus coeruleus from the periaqueductal gray and rostroventral medulla shape opioid-mediated descending pain modulation
ST Lubejko, G Livrizzi, SA Buczynski, J Patel… - Science …, 2024 - science.org
… the rostroventromedial medulla (RVM), the suppression of which disinhibits LC neurons to
drive spinal noradrenergic antinociception. We describe pain-… of descending pain modulation. …
drive spinal noradrenergic antinociception. We describe pain-… of descending pain modulation. …
Endovanilloid control of pain modulation by the rostroventromedial medulla in an animal model of diabetic neuropathy
… In order to study the role of endovanilloid signalling in RVM-mediated pain modulation in
an experimental model of DNP, we evaluated the local expression of TRPV1 and FAAH and …
an experimental model of DNP, we evaluated the local expression of TRPV1 and FAAH and …
Shifting the Balance: How Top-Down and Bottom-Up Input Modulate Pain via the Rostral Ventromedial Medulla
Q Chen, MM Heinricher - Frontiers in Pain Research, 2022 - frontiersin.org
… Understanding the interaction between these inputs and defined RVM cell classes will
continue to elucidate central mechanisms of pain modulation. This may ultimately make it …
continue to elucidate central mechanisms of pain modulation. This may ultimately make it …
Serotoninergic pain modulation from the rostral ventromedial medulla (RVM) in chemotherapy‐induced neuropathy: the role of spinal 5‐HT3 receptors
JT Costa‐Pereira, P Serrão, I Martins… - European Journal of …, 2020 - Wiley Online Library
… In conclusion, we showed increased descending 5-HT-mediated pain modulation from
the RVM and increased of the facilitatory role of spinal 5-HT3R. This may underlie the …
the RVM and increased of the facilitatory role of spinal 5-HT3R. This may underlie the …
The role of the rostral ventromedial medulla in stress responses
M Pagliusi Jr, FV Gomes - Brain Sciences, 2023 - mdpi.com
… The rostral ventromedial medulla (RVM) is a brainstem structure critical for the descending
pain modulation system involved in both pain facilitation and inhibition through its projection …
pain modulation system involved in both pain facilitation and inhibition through its projection …
The cellular mechanism by which the rostral ventromedial medulla acts on the spinal cord during chronic pain
Y WeiWei, F WenDi, C Mengru, Y Tuo… - Reviews in the …, 2021 - degruyter.com
… pain partly results from central changes caused by alterations in neurons in the rostral
ventromedial medulla (… The output of descending pain-modulating pathway can be influenced by …
ventromedial medulla (… The output of descending pain-modulating pathway can be influenced by …
… evidence for a direct circuit linking nociceptive transmission through the parabrachial complex with pain-modulating neurons of the rostral ventromedial medulla (RVM …
… pain-modulating systems, the best characterized of which is the rostral ventromedial medulla
… direct, functionally relevant inputs to RVM pain-modulating neurons from PB. Whole-cell …
… direct, functionally relevant inputs to RVM pain-modulating neurons from PB. Whole-cell …
Cortical and subcortical modulation of pain
MD Felice, MH Ossipov - Pain management, 2016 - Taylor & Francis
… pain modulation arising from the periaqueductal gray (PAG) and activating the rostral
ventromedial medulla (RVM) and noradrenergic nuclei to block ascending nociceptive inputs. …
ventromedial medulla (RVM) and noradrenergic nuclei to block ascending nociceptive inputs. …
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