Erlotinib, cabozantinib, or erlotinib plus cabozantinib as second-line or third-line treatment of patients with EGFR wild-type advanced non-small-cell lung cancer …

JW Neal, SE Dahlberg, HA Wakelee, SC Aisner… - The Lancet …, 2016 - thelancet.com
patients to erlotinib treatment, 40 patients to cabozantinib treatment, and 43 patients to erlotinib
… (erlotinib [n=38], cabozantinib [n=38], erlotinib plus cabozantinib [n=35]). Compared with …

Afatinib versus erlotinib as second-line treatment of patients with advanced squamous cell carcinoma of the lung: Final analysis of the randomised phase 3 LUX-Lung …

GD Goss, M Cobo, S Lu, K Syrigos, KH Lee… - …, 2021 - thelancet.com
… 8, an open-label phase III study of second-line afatinib versus erlotinib in patients with
advanced squamous cell carcinoma of the lung after first-line platinum-based chemotherapy. …

[HTML][HTML] … III study of second-line afatinib versus erlotinib in patients with advanced squamous cell carcinoma of the lung after first-line platinum-based chemotherapy

E Felip, V Hirsh, S Popat, M Cobo, A Fülöp, C Dayen… - Clinical Lung Cancer, 2018 - Elsevier
… In summary, second-line afatinib significantly improved symptoms of … with erlotinib in patients
with SCC of the lung. Mean scores over time also significantly favored afatinib over erlotinib

… phase III study of combining erlotinib with bevacizumab and panitumumab versus erlotinib alone as second-line therapy for Chinese patients with non-small-cell lung …

Y Wang, H Wang, Y Jiang, Y Zhang, X Wang - Biomedicine & …, 2017 - Elsevier
second-line chemotherapies between erlotinib plus bevacizumab and panitumumab, and
erlotinib … The goal of our study was to explore optimal second-line treatment option for patients

[HTML][HTML] Maintenance erlotinib versus erlotinib at disease progression in patients with advanced non-small-cell lung cancer who have not progressed following …

S Cicènas, SL Geater, P Petrov, Y Hotko, G Hooper… - Lung Cancer, 2016 - Elsevier
… (OS) with maintenance erlotinib versus second-line erlotinib. Secondary objectives of the …
rate (DCR) between the study arms (erlotinib vs. placebo) during the blinded maintenance …

Cost–effectiveness of afatinib and erlotinib as second-line treatments for advanced squamous cell carcinoma of the lung

J Zhu, W He, M Ye, J Fu, YB Chu, YY Zhao… - Future …, 2018 - Taylor & Francis
… The indication of afatinib and erlotinib for SqCC of the lung had not been approved.
However, because the oncologist and patients would still pursue these agents as second-line

First-line erlotinib therapy until and beyond response evaluation criteria in solid tumors progression in Asian patients with epidermal growth factor receptor mutation …

K Park, CJ Yu, SW Kim, MC Lin, V Sriuranpong… - JAMA …, 2016 - jamanetwork.com
erlotinib therapy may be most beneficial in patients with good response to first-line erlotinib,
… In brief, it is conceivable that patients with slow PD could benefit from continuation of EGFR …

… and secondary epidermal growth factor receptor (EGFR) T790M mutation among first‐line gefitinib, erlotinib and afatinib‐treated non‐small cell lung cancer patients …

YT Lin, JS Chen, WY Liao, CC Ho… - … Journal of Cancer, 2019 - Wiley Online Library
… Our study retrospectively enrolled patients who had received gefitinib, erlotinib or afatinib
for first-line treatment of stage IV or post-operative recurrent (advanced) NSCLC between 2014/…

Erlotinib as second‑or third‑line treatment in elderly patients with advanced non‑small cell lung cancer: Keio Lung Oncology Group Study 001 (KLOG001)

M Miyawaki, K Naoki, S Yoda… - Molecular and …, 2017 - spandidos-publications.com
… phase II trial of second- or third-line erlotinib treatment in elderly patients with NSCLC. The
primary endpoint was overall response rate (ORR) and the secondary endpoints were PFS, …

A randomized, double-blind, phase III study comparing two doses of erlotinib for second-line treatment of current smokers with advanced non-small-cell lung cancer …

EF Smit, YL Wu, R Gervais, C Zhou, E Felip, J Feng… - Lung Cancer, 2016 - Elsevier
erlotinib metabolism versus non-smoking patients, which reduces exposure. Therefore, an
increased erlotinib … and safety of 300 mg erlotinib (E300) as second-line therapy in current …