[HTML][HTML] Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation

J Zhou, RL Sears, X Xing, B Zhang, D Li… - BMC genomics, 2017 - Springer
… Conserved DNA methylation is associated with conservation of … conservation of primary
genomic sequences. We found that the evolutionary dynamics of tissue-specific DNA methylation

[HTML][HTML] A comparative methylome analysis reveals conservation and divergence of DNA methylation patterns and functions in vertebrates

H Al Adhami, AF Bardet, M Dumas, E Cleroux… - BMC biology, 2022 - Springer
… We analyze the evolutionary conservation of DNA methylation … of DNA methylation in
vertebrate cells by DNA methylation … CG-rich sequences are more frequently methylated in germ …

Beyond restriction modification: epigenomic roles of DNA methylation in prokaryotes

BP Anton, RJ Roberts - Annual Review of Microbiology, 2021 - annualreviews.org
… , DNA methylation is an epigenetic signal capable of altering the interpretation of genetic
information without change to the DNA sequence itself. … far less sequence conservation than the …

Evolutionary conservation of DNA methylation in CpG sites within ultraconserved noncoding elements

M Colwell, M Drown, K Showel, C Drown, A Palowski… - Epigenetics, 2018 - Taylor & Francis
… Despite extreme sequence conservationDNA methylation in these regions. Here, we
surveyed UCNEs with high CpG density in 56 species finding half to be intermediately methylated

Comparative epigenomics: a powerful tool to understand the evolution of DNA methylation

X Zhong - New Phytologist, 2016 - Wiley Online Library
DNA methylation from an evolutionary perspective. Using comparative approaches, I highlight
the conservation and divergence of DNA methylation … -throughput sequencing technology …

[HTML][HTML] Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods

SH Lewis, L Ross, SA Bain, E Pahita, SA Smith… - PLoS …, 2020 - journals.plos.org
… on a genome-wide scale, we carried out whole-genome bisulphite sequencing. We used
the DNeasy Blood and Tissue kit (QIAGEN) according to the manufacturer’s protocol to extract …

The diverse roles of DNA methylation in mammalian development and disease

MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… of DNA methylation in embryonic, germline and somatic cell development. Finally, we
provide insights into DNA methylation … recognize and bind DNA methylated sequences (reviewed …

Protection of CpG islands from DNA methylation is DNA-encoded and evolutionarily conserved

HK Long, HW King, RK Patient, DT Odom… - Nucleic Acids …, 2016 - academic.oup.com
… -restricted repeat sequences that evaded DNA methylation in the … methylation to these
sequences, and species specific DNA binding events that protected against DNA methylation in …

[HTML][HTML] DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning

C Angermueller, HJ Lee, W Reik, O Stegle - Genome biology, 2017 - Springer
… Globally, we observed a negative correlation between mutational effects and DNA sequence
conservation (P < 1.0 × 10 −15 ; Additional file 1: Figure S13), providing evidence that …

Conserved DNA methyltransferases: a window into fundamental mechanisms of epigenetic regulation in bacteria

PH Oliveira, G Fang - Trends in microbiology, 2021 - cell.com
sequence. Instead, significant meaning can also be conveyed through the epigenetic states
of DNA (eg, by chemical modification such as DNA methylation)… of DNA MTase conservation