[HTML][HTML] Tissue-specific DNA methylation is conserved across human, mouse, and rat, and driven by primary sequence conservation
… Conserved DNA methylation is associated with conservation of … conservation of primary
genomic sequences. We found that the evolutionary dynamics of tissue-specific DNA methylation …
genomic sequences. We found that the evolutionary dynamics of tissue-specific DNA methylation …
[HTML][HTML] A comparative methylome analysis reveals conservation and divergence of DNA methylation patterns and functions in vertebrates
H Al Adhami, AF Bardet, M Dumas, E Cleroux… - BMC biology, 2022 - Springer
… We analyze the evolutionary conservation of DNA methylation … of DNA methylation in
vertebrate cells by DNA methylation … CG-rich sequences are more frequently methylated in germ …
vertebrate cells by DNA methylation … CG-rich sequences are more frequently methylated in germ …
Beyond restriction modification: epigenomic roles of DNA methylation in prokaryotes
BP Anton, RJ Roberts - Annual Review of Microbiology, 2021 - annualreviews.org
… , DNA methylation is an epigenetic signal capable of altering the interpretation of genetic
information without change to the DNA sequence itself. … far less sequence conservation than the …
information without change to the DNA sequence itself. … far less sequence conservation than the …
Evolutionary conservation of DNA methylation in CpG sites within ultraconserved noncoding elements
… Despite extreme sequence conservation … DNA methylation in these regions. Here, we
surveyed UCNEs with high CpG density in 56 species finding half to be intermediately methylated …
surveyed UCNEs with high CpG density in 56 species finding half to be intermediately methylated …
Comparative epigenomics: a powerful tool to understand the evolution of DNA methylation
X Zhong - New Phytologist, 2016 - Wiley Online Library
… DNA methylation from an evolutionary perspective. Using comparative approaches, I highlight
the conservation and divergence of DNA methylation … -throughput sequencing technology …
the conservation and divergence of DNA methylation … -throughput sequencing technology …
[HTML][HTML] Widespread conservation and lineage-specific diversification of genome-wide DNA methylation patterns across arthropods
… on a genome-wide scale, we carried out whole-genome bisulphite sequencing. We used
the DNeasy Blood and Tissue kit (QIAGEN) according to the manufacturer’s protocol to extract …
the DNeasy Blood and Tissue kit (QIAGEN) according to the manufacturer’s protocol to extract …
The diverse roles of DNA methylation in mammalian development and disease
MVC Greenberg, D Bourc'his - Nature reviews Molecular cell biology, 2019 - nature.com
… of DNA methylation in embryonic, germline and somatic cell development. Finally, we
provide insights into DNA methylation … recognize and bind DNA methylated sequences (reviewed …
provide insights into DNA methylation … recognize and bind DNA methylated sequences (reviewed …
Protection of CpG islands from DNA methylation is DNA-encoded and evolutionarily conserved
… -restricted repeat sequences that evaded DNA methylation in the … methylation to these
sequences, and species specific DNA binding events that protected against DNA methylation in …
sequences, and species specific DNA binding events that protected against DNA methylation in …
[HTML][HTML] DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning
… Globally, we observed a negative correlation between mutational effects and DNA sequence
conservation (P < 1.0 × 10 −15 ; Additional file 1: Figure S13), providing evidence that …
conservation (P < 1.0 × 10 −15 ; Additional file 1: Figure S13), providing evidence that …
Conserved DNA methyltransferases: a window into fundamental mechanisms of epigenetic regulation in bacteria
PH Oliveira, G Fang - Trends in microbiology, 2021 - cell.com
… sequence. Instead, significant meaning can also be conveyed through the epigenetic states
of DNA (eg, by chemical modification such as DNA methylation)… of DNA MTase conservation …
of DNA (eg, by chemical modification such as DNA methylation)… of DNA MTase conservation …
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