… They expanded the list of diagnostic criteria but the current concepts of sepsis, severe sepsis
and septic shock were only slightly revised and they remained the basis for clinical practice …

… Thus, the old ‘severe sepsis’ becomes ‘sepsis’ with the new … The most severe form of sepsis
is septic shock, a state of … therapy,60-63 improve outcomes for patients with septic shock. …

… considered vasodilator therapy, in patients with sepsis and … of patients with severe sepsis
and septic shock are not fluid … ’ of patients with severe sepsis and septic shock needs to be …

… of sepsis immune pathophysiology, to update the choice of therapeutic approaches targeting
… , which enrolled more than thousand severe sepsis and septic shock patients, it was shown …

… outcomes with this approach, Surviving Sepsis guidelines now … for patients with severe
sepsis or septic shock found that … substantially from therapeutic approaches derived from …

… Several new approaches have been reported to reduce mortality rates in severe sepsis. …
In addition, we experimentally investigated several new therapeutic targets such as 5-HT7 …

… nature of sepsis, guiding toward new definition and novel therapeutic approaches. Diverse
… In a latest global survey of pediatric sepsis, severe sepsis remains a leading cause of death …

… In this study, levels of syndecan-1 have been evaluated in 104 patients suffering from
severe sepsis or septic shock, in 28 patients after major abdominal surgery and in 18 healthy …

… by severe coronavirus disease 2019 patients and sepsis and describe proposed anti-inflammatory
therapies … and improving the 28-day survival rate of patients with severe sepsis ( 31 ). …

… different therapeutic approaches to improve patient outcomes. Rescue strategies for septic
shock may … Distinguishing between phenotypes in patients with severe septic shock based on …