Role of the NFκB-signaling pathway in cancer

L Xia, S Tan, Y Zhou, J Lin, H Wang… - OncoTargets and …, 2018 - Taylor & Francis
… , and VEGF, NFκB mediates tumor-cell proliferation, survival, and angiogenesis. Citation9
This … focuses on this NFκB-signaling pathway in tumors. Overview of NFκB-signaling pathways

Signaling via the NFκB system

S Mitchell, J Vargas, A Hoffmann - … Reviews: Systems Biology …, 2016 - Wiley Online Library
… The canonical NFκB signaling pathway (aka NEMO-dependent pathway) is mediated by
kinase complexes consisting of the scaffold/adaptor protein NEMO (aka IKKγ) and two IκB …

NF-κB signaling in inflammation

T Liu, L Zhang, D Joo, SC Sun - Signal transduction and targeted …, 2017 - nature.com
… The activation of NF-κB involves two major signaling pathways, … NF-κB pathway appears
to be evolved as a supplementary signaling axis that cooperates with canonical NF-κB pathway

Role of the NF-κB signaling pathway in the pathogenesis of colorectal cancer

A Soleimani, F Rahmani, GA Ferns, M Ryzhikov… - Gene, 2020 - Elsevier
… Over-activation of the NF-κB pathway is a feature of colorectal … Suppression of the NF-κB
signaling pathway using biological or … the regulatory role of NF-κB signaling pathway in the …

NF-κB signaling pathways in osteoarthritic cartilage destruction

MC Choi, J Jo, J Park, HK Kang, Y Park - Cells, 2019 - mdpi.com
… of the functions or regulation of NF-κB in the OA pathology will aid … of NF-κB in OA chondrocytes
and related signaling pathways, … that can interfere with NF-κB signaling for OA treatment. …

Crosstalk between Wnt/β-Catenin and NF-κB signaling pathway during inflammation

B Ma, MO Hottiger - Frontiers in immunology, 2016 - frontiersin.org
… regulation of NF-κB-mediated inflammation by Wnt/β-catenin signaling and elaborate on …
signaling by the NF-κB pathway and novel models for the cooperation of these two pathways in …

NF-κB signaling pathway and its potential as a target for therapy in lymphoid neoplasms

L Yu, L Li, LJ Medeiros, KH Young - Blood reviews, 2017 - Elsevier
… of the NF-κB pathway and its signaling components … NF-κB functions as a crucial modulator
of the extrinsic B-cell tissue microenvironment (TME) and intrinsic survival signaling pathways

NFκB signaling in inflammation and cancer

T Zhang, C Ma, Z Zhang, H Zhang, H Hu - MedComm, 2021 - Wiley Online Library
… members of NF-κB, as well as the basic mechanisms of NF-κB signaling pathway activation.
We … The NF-κB activation signaling pathways have been well studied. There are two types of …

Advancement of NF-κB signaling pathway: a novel target in pancreatic cancer

KC Pramanik, MR Makena, K Bhowmick… - International journal of …, 2018 - mdpi.com
… involvement of NF-κB in PADC’s progression and resistance. We also highlighted the
interaction of NF-κB with other signaling pathways. Lastly, we also aim to discuss how NF-κB could …

The NF-κB signaling pathway, the microbiota, and gastrointestinal tumorigenesis: recent advances

C Peng, Y Ouyang, N Lu, N Li - Frontiers in Immunology, 2020 - frontiersin.org
NF-κB plays a crucial role in the host response to microbial infection through orchestrating
innate and adaptive immune functions. Moreover, NF-κB … of the NF-κB signaling pathway by …