Effect of aberrant DNA methylation on cancer stem cell properties
… properties such as self-regeneration, resistance to … DNA methylation accumulation affects
self-renewal, differentiation, multidrug-resistant, and metastasis processes in cancer stem cells. …
self-renewal, differentiation, multidrug-resistant, and metastasis processes in cancer stem cells. …
DNA methylation: an epigenetic mark of cellular memory
M Kim, J Costello - Experimental & molecular medicine, 2017 - nature.com
… DNA methylation has critical roles in the maintenance of stem cell identity and lineage …
In this section, we describe DNA methylation as an epigenetic memory of stem cells such as …
In this section, we describe DNA methylation as an epigenetic memory of stem cells such as …
Proteins in DNA methylation and their role in neural stem cell proliferation and differentiation
… Significant advances to identify the dynamic roles of DNA methylation in brain development
have been made. In this review, we highlight DNA methylation and DNA demethylation, …
have been made. In this review, we highlight DNA methylation and DNA demethylation, …
DNA methylation in skeletal muscle stem cell specification, proliferation, and differentiation
RC Laker, JG Ryall - Stem cells international, 2016 - Wiley Online Library
… and in particular DNA methylation, in the regulation of stem cell identity, this … methylation,
with a particular focus on skeletal muscle stem cells (MuSCs, also referred to as satellite cells). …
with a particular focus on skeletal muscle stem cells (MuSCs, also referred to as satellite cells). …
Impairment of DNA methylation maintenance is the main cause of global demethylation in naive embryonic stem cells
… methylation in mouse embryonic stem cells in which one or more of the components of the
DNA methylation … To this end, we determined the DNA methylation state at several time points …
DNA methylation … To this end, we determined the DNA methylation state at several time points …
YAP contributes to DNA methylation remodeling upon mouse embryonic stem cell differentiation
F Passaro, I De Martino, F Zambelli… - Journal of Biological …, 2021 - ASBMB
… in undifferentiated ESCs (T0) versus cells … DNA methylation occurring in CTR cells upon
4 days of differentiation, compared with CTR cells at T0, finding 6661 differentially methylated …
4 days of differentiation, compared with CTR cells at T0, finding 6661 differentially methylated …
Differential DNA methylation encodes proliferation and senescence programs in human adipose-derived mesenchymal stem cells
… cellular processes that are responsive to 5′-azacitidine (5′-AZA). We describe specific
changes to DNA methylation … We identified 4,797 differentially methylated regions (FDR < 0.05) …
changes to DNA methylation … We identified 4,797 differentially methylated regions (FDR < 0.05) …
DNA methylation entropy as a measure of stem cell replication and aging
… DNA methylation with age in mouse intestinal stem cells and compare them to nonstem
cells… age-related DNA methylation drift is attributable to adult stem cell replication. Analysis of …
cells… age-related DNA methylation drift is attributable to adult stem cell replication. Analysis of …
Ageing affects DNA methylation drift and transcriptional cell-to-cell variability in mouse muscle stem cells
I Hernando-Herraez, B Evano, T Stubbs… - Nature …, 2019 - nature.com
… genes regulating cell-niche interactions. We find context-dependent alterations of DNA
methylation in aged stem cells. Importantly, promoters with increased methylation heterogeneity …
methylation in aged stem cells. Importantly, promoters with increased methylation heterogeneity …
Tracing human stem cell lineage during development using DNA methylation
… Stem cell maturation is a fundamental, yet poorly understood aspect of human development…
a DNA methylation signature deeply reminiscent of embryonic stem cells (a fetal cell origin …
a DNA methylation signature deeply reminiscent of embryonic stem cells (a fetal cell origin …
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