An efficient platform for astrocyte differentiation from human induced pluripotent stem cells
… rapid and robust method for the differentiation of highly pure populations of replicative
astrocytes from human induced pluripotent stem cells (hiPSCs), via a neural progenitor cell (NPC) …
astrocytes from human induced pluripotent stem cells (hiPSCs), via a neural progenitor cell (NPC) …
Astrocyte differentiation of human pluripotent stem cells: new tools for neurological disorder research
A Chandrasekaran, HX Avci, M Leist… - Frontiers in cellular …, 2016 - frontiersin.org
… on astrocytes continues, and our understanding of their disease-relevant cellular functions in
… Here, we review the role of astrocytes, compare their in vivo and in vitro differentiation, and …
… Here, we review the role of astrocytes, compare their in vivo and in vitro differentiation, and …
Understanding astrocyte differentiation: Clinical relevance, technical challenges, and new opportunities in the omics era
M Lattke, F Guillemot - WIREs Mechanisms of Disease, 2022 - Wiley Online Library
… of adult astrocytes. … of astrocyte differentiation and maturation, due to biological and technical
challenges, including the high degree of similarity of astrocytes with neural stem cells and …
challenges, including the high degree of similarity of astrocytes with neural stem cells and …
[HTML][HTML] A defined roadmap of radial glia and astrocyte differentiation from human pluripotent stem cells
… of astrocytes from human pluripotent stem cells (hPSCs) is inefficient and cumbersome. Here,
we report controlled glial differentiation from … and in vitro differentiation. hPSCs were first …
we report controlled glial differentiation from … and in vitro differentiation. hPSCs were first …
Neurosphere based differentiation of human iPSC improves astrocyte differentiation
S Zhou, K Szczesna, A Ochalek, J Kobolák… - Stem Cells …, 2016 - Wiley Online Library
… to 2D derived cells (Figure 5(d)). Subsequently, to confirm that 3D culture system promotes
astrocyte differentiation we evaluate the expression of another astrocyte marker aquaporin 4 (…
astrocyte differentiation we evaluate the expression of another astrocyte marker aquaporin 4 (…
Zika virus induces astrocyte differentiation in neural stem cells
OV Lossia, MJ Conway, MO Tree, RJ Williams… - Journal of …, 2018 - Springer
… astrocytes differentiated from mouse neural stem cells. Astrocytes differentiated from mouse
neural stem cells were mock- or ZIKV-infected and total cellular RNA was extracted 7 days …
neural stem cells were mock- or ZIKV-infected and total cellular RNA was extracted 7 days …
Identification of the gliogenic state of human neural stem cells to optimize in vitro astrocyte differentiation
M Alisch, J Kerkering, T Crowley, K Rosiewicz… - Journal of Neuroscience …, 2021 - Elsevier
… astrocytes in vitro represents a major roadblock for glial cell research. We show that rapid and
robust astrocyte differentiation … the signature of a novel gliogenic stem cell population. The …
robust astrocyte differentiation … the signature of a novel gliogenic stem cell population. The …
NF-κB and TNF affect the astrocytic differentiation from neural stem cells
C Birck, A Ginolhac, MAS Pavlou, A Michelucci… - Cells, 2021 - mdpi.com
… differentiation of NPCs into astrocytes. First, we show that the NF-κB pathway is essential to
initiate astrocytic differentiation … NPC apoptosis and impedes their differentiation. Second, we …
initiate astrocytic differentiation … NPC apoptosis and impedes their differentiation. Second, we …
Hippocalcin promotes neuronal differentiation and inhibits astrocytic differentiation in neural stem cells
SY Park, SN Yoon, MJ Kang, YY Lee, SJ Jung, JS Han - Stem cell reports, 2017 - cell.com
… HPCA inhibits astrocytic differentiation of neural stem cells. It … which is necessary for astrocytic
differentiation. Moreover, we … HPCA promotes neuronal differentiation through activation of …
differentiation. Moreover, we … HPCA promotes neuronal differentiation through activation of …
β1‐integrin restricts astrocytic differentiation of adult hippocampal neural stem cells
… adult hippocampal stem cell niche in male and female mice. … stem cell niche and by inhibiting
astrocytic differentiation. … β1-integrin ablation on SGZ structure and NSC differentiation. …
astrocytic differentiation. … β1-integrin ablation on SGZ structure and NSC differentiation. …
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