Comparison of gefitinib, erlotinib and afatinib in non‐small cell lung cancer: a meta‐analysis

Z Yang, A Hackshaw, Q Feng, X Fu… - … journal of cancer, 2017 - Wiley Online Library
… efficacy than gefitinib or erlotinib in first-line treatment of EGFR-… effective than erlotinib as
second-line treatment of patients with … studies, with emphasis on comparability between gefitinib

[HTML][HTML] A comparative study on erlotinib & gefitinib therapy in non-small cell lung carcinoma patients

P Thomas, B Vincent, C George… - … of Medical Research, 2019 - journals.lww.com
study showed that erlotinib and gefitinib had similar effectiveness but gefitinib had a better
safety profile compared to erlotiniberlotinib and gefitinib for treating NSCLC in our study

[HTML][HTML] A phase III randomised controlled trial of erlotinib vs gefitinib in advanced non-small cell lung cancer with EGFR mutations

JJ Yang, Q Zhou, HH Yan, XC Zhang, HJ Chen… - British journal of …, 2017 - nature.com
Treatment schedule … at a 1 : 1 ratio to receive oral erlotinib 150 mg or gefitinib 250 mg once
daily. Second- and further-line treatments were defined as second line in the present study. …

[HTML][HTML] Risk of treatment-related toxicities from EGFR tyrosine kinase inhibitors: a meta-analysis of clinical trials of gefitinib, erlotinib, and afatinib in advanced EGFR …

PN Ding, SJ Lord, V Gebski, M Links, V Bray… - Journal of Thoracic …, 2017 - Elsevier
… entry, because we recognized that a significant proportion of patients included in this
study did not have EGFR activating mutation and may have had a shorter duration of …

Gefitinib or erlotinib in previously treated non–small‐cell lung cancer patients: a cohort study in Taiwan

CH Chang, CH Lee, JC Ko, LY Chang… - Cancer …, 2017 - Wiley Online Library
… The EGFR-TKIs investigated in this study were gefitinib and erlotinib. Afatinib had not yet
been approved by NHI during the study period. The prescription duration of individual EGFR-…

[HTML][HTML] Comparison of the effectiveness of erlotinib, gefitinib, and afatinib for treatment of non‑small cell lung cancer in patients with common and rare EGFR gene …

P Krawczyk, DM Kowalski, R Ramlau… - Oncology …, 2017 - spandidos-publications.com
… This study was the first to directly compare EGFR-TKIs treatment efficacy in … erlotinib- and
gefitinib-treated groups (11.7 vs. 14.5 months; P=0.507) in a retrospective case-control study of …

[HTML][HTML] A retrospective comparison of the clinical efficacy of gefitinib, erlotinib, and afatinib in Japanese patients with non-small cell lung cancer

A Fujiwara, M Yoshida, H Fujimoto, H Nakahara… - … research, 2018 - ncbi.nlm.nih.gov
… -line therapy is still a controversial issue. The aim of this study was to compare the effectiveness
of gefitinib, erlotinib, and … NSCLC including 147 patients treated with EGFR TKIs. Time to …

[HTML][HTML] Efficacy and safety of afatinib for EGFR-mutant non-small cell lung cancer, compared with gefitinib or erlotinib

Y Kim, SH Lee, JS Ahn, MJ Ahn, K Park… - … and Treatment: Official …, 2019 - ncbi.nlm.nih.gov
therapy for EGFR-mutant NSCLC was first reimbursed in Korea (October 2014). Our purpose
of this study is to … it leads to different clinical outcomes compared with gefitinib or erlotinib. …

Gefitinib or Erlotinib vs Chemotherapy for EGFR Mutation-Positive Lung Cancer: Individual Patient Data Meta-Analysis of Overall Survival

CK Lee, L Davies, YL Wu, T Mitsudomi… - JNCI: Journal of the …, 2017 - academic.oup.com
study, the primary objective was to determine the pooled overall treatment effect on OS of
firstline therapy with gefitinib … this meta-analysis of gefitinib and erlotinib as most of the included …

[HTML][HTML] A phase III, randomized, open-label study of ASP8273 versus erlotinib or gefitinib in patients with advanced stage IIIB/IV non-small-cell lung cancer

RJ Kelly, FA Shepherd, A Krivoshik, F Jie, L Horn - Annals of Oncology, 2019 - Elsevier
… , but patients with exon 20 point mutations from another phase I study (NCT02113813)
without available standard-of-care therapies could continue ASP8273 under revised consent …