Erlotinib
M Steins, M Thomas, M Geißler - Small molecules in oncology, 2018 - Springer
… median survival, 31% of patients treated with erlotinib in this study were alive at 1 year versus
22… PFS for the gefitinib-treated patient group compared to carboplatin/paclitaxel in first-line …
22… PFS for the gefitinib-treated patient group compared to carboplatin/paclitaxel in first-line …
Clinical outcomes of gefitinib and erlotinib in patients with NSCLC harboring uncommon EGFR mutations: A pooled analysis of 438 patients
C Wang, K Zhao, S Hu, W Dong, Y Gong, M Li, C Xie - Lung Cancer, 2022 - Elsevier
… In the current study, we analyzed the treatment response and … study, patients treated
with gefitinib had a significantly better ORR and longer PFS than those treated with erlotinib…
with gefitinib had a significantly better ORR and longer PFS than those treated with erlotinib…
Erlotinib and gefitinib responsiveness in head and neck cancer cell lines—a comparing analysis with cetuximab
S Hartmann, N Neckel, A Seher, G Mutzbauer… - Clinical oral …, 2016 - Springer
… this study is to examine the efficacy of erlotinib and gefitinib … to cetuximab, erlotinib and
gefitinib treatment resulted in … the efficacy of erlotinib or gefitinib treatment was significantly …
gefitinib treatment resulted in … the efficacy of erlotinib or gefitinib treatment was significantly …
Randomized phase II study of fulvestrant and erlotinib compared with erlotinib alone in patients with advanced or metastatic non-small cell lung cancer
EB Garon, JM Siegfried, LP Stabile, PA Young… - Lung Cancer, 2018 - Elsevier
… The four patients enrolled when gefitinib was the EGFR inhibitor … Thus, although this study
endured slow patient accrual … treated with erlotinib and fulvestrant as compared to erlotinib …
endured slow patient accrual … treated with erlotinib and fulvestrant as compared to erlotinib …
Combining nonclinical experiments with translational PKPD modeling to differentiate erlotinib and gefitinib
… In this study, we compare two TKIs, erlotinib and gefitinib (10), based on their PKPD
properties (11). Both compounds are orally administered to treat epidermoid cancers with high …
properties (11). Both compounds are orally administered to treat epidermoid cancers with high …
… of efficacy and safety of erlotinib as first-line TKI treatment in EGFR mutation-positive advanced non-small cell lung cancer: Results from the EGFR-2013-CPHG study
T Payen, J Trédaniel, L Moreau, S Larivé… - … Medicine and Research, 2021 - Elsevier
… treatment of non-small cell lung cancer (NSCLC) patients with EGFR-activating mutations.
Using a cohort of unselected patients treated with erlotinib, … mutations (erlotinib, gefitinib, and …
Using a cohort of unselected patients treated with erlotinib, … mutations (erlotinib, gefitinib, and …
[HTML][HTML] Effectiveness and safety of afatinib, gefitinib, and erlotinib for treatment-naïve elderly patients with epidermal growth factor receptor-mutated advanced non …
LJ Hung, PC Hsu, CT Yang, CHS Kuo… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
… for EGFR-TKI treatment of elderly patients is also limited. Therefore, this study aimed to
describe the effectiveness and safety of afatinib, gefitinib, and erlotinib for treatment-naïve elderly …
describe the effectiveness and safety of afatinib, gefitinib, and erlotinib for treatment-naïve elderly …
Which is better EGFR-TKI followed by osimertinib: afatinib or gefitinib/erlotinib?
M Tamiya, A Tamiya, H Suzuki, K Moriizumi… - … Research, 2019 - ar.iiarjournals.org
… in patients who received a 3rd-G EGFR-TKI following discontinuation of study treatment was
not … we conducted in this study. Our results showed that treatment with osimertinib following …
not … we conducted in this study. Our results showed that treatment with osimertinib following …
Repeat biopsy procedures and T790M rates after afatinib, gefitinib, or erlotinib therapy in patients with lung cancer
K Lee, Y Kim, HA Jung, SH Lee, JS Ahn, MJ Ahn… - Lung cancer, 2019 - Elsevier
… aims of this study are to evaluate resistance mechanisms of afatinib compared with other
TKIs and analyze the performance of repeat biopsy which is critical for subsequent treatment. …
TKIs and analyze the performance of repeat biopsy which is critical for subsequent treatment. …