Fundamentals of bicarbonate secretion in epithelia
I Novak, J Praetorius - Basic Epithelial Ion Transport Principles and …, 2020 - Springer
… of epithelia in our body secrete significant amount of HCO 3 − , which is often accompanied
by fluid secretion. … , such as the stomach surface cells, duodenum, colon, and choroid plexus. …
by fluid secretion. … , such as the stomach surface cells, duodenum, colon, and choroid plexus. …
Concurrent absorption and secretion of airway surface liquids and bicarbonate secretion in human bronchioles
AKM Shamsuddin, PM Quinton - American Journal of …, 2019 - journals.physiology.org
… epithelia that would support simultaneous secretion and absorption of the ASL. In addition,
we sought to determine whether the small airway epithelium also secretes bicarbonate …
we sought to determine whether the small airway epithelium also secretes bicarbonate …
Bicarbonate transport of airway surface epithelia in luminally perfused mice bronchioles
L Liu, A Yamamoto, M Yamaguchi, I Taniguchi… - The Journal of …, 2022 - Springer
… secretion in distal airways is critical for airway mucosal defense. HCO 3 − /H + transport across
the apical membrane of airway surface epithelial … 3 − transport in surface epithelial cells of …
the apical membrane of airway surface epithelial … 3 − transport in surface epithelial cells of …
Paracellular bicarbonate flux across human cystic fibrosis airway epithelia tempers changes in airway surface liquid pH
IM Thornell, T Rehman, AA Pezzulo… - The Journal of …, 2020 - Wiley Online Library
… Airway epithelia control the pH of airway surface liquid (ASL), thereby optimizing respiratory
defences. Active H + and HCO 3 − secretion by airway epithelial cells produce an ASL that …
defences. Active H + and HCO 3 − secretion by airway epithelial cells produce an ASL that …
Pendrin mediates bicarbonate secretion and enhances cystic fibrosis transmembrane conductance regulator function in airway surface epithelia
… current by approximately twofold in epithelial and nonepithelial cells. We … secretion across
airway surface epithelium during inflammation and enhances electrogenic Cl − secretion …
airway surface epithelium during inflammation and enhances electrogenic Cl − secretion …
Bicarbonate secretion and acid/base sensing by the intestine
HM Becker, UE Seidler - Pflügers Archiv-European Journal of Physiology, 2024 - Springer
… Major advances have been made in the assessment of surface epithelial function using
video-imaging and two-photon techniques to assess the intracellular and juxtamucosal pH in …
video-imaging and two-photon techniques to assess the intracellular and juxtamucosal pH in …
Airway surface liquid pH regulation in airway epithelium current understandings and gaps in knowledge
M Zajac, E Dreano, A Edwards, G Planelles… - International journal of …, 2021 - mdpi.com
… The latter mainly involves CFTR, the apical chloride/bicarbonate exchanger pendrin and
paracellular transport. Proton (H + ) secretion into ASL is crucial to maintain its relative acidity …
paracellular transport. Proton (H + ) secretion into ASL is crucial to maintain its relative acidity …
[HTML][HTML] Bicarbonate in cystic fibrosis
K Kunzelmann, R Schreiber, HB Hadorn - Journal of Cystic Fibrosis, 2017 - Elsevier
… of anion secretion is a common feature of epithelial organs … CF airway epithelia were also
shown to absorb airway surface … urinary bicarbonate excretion at different serum bicarbonate …
shown to absorb airway surface … urinary bicarbonate excretion at different serum bicarbonate …
The fundamental role of bicarbonate transporters and associated carbonic anhydrase enzymes in maintaining ion and pH homeostasis in non-secretory organs
… Duodenal, intestinal, and colonic HCO 3 − regulation is crucial for epithelial defense against
acid and for mucus secretion, as well as for pH regulation [125,126,127]. Several reports …
acid and for mucus secretion, as well as for pH regulation [125,126,127]. Several reports …
[HTML][HTML] Hepatobiliary acid-base homeostasis: Insights from analogous secretory epithelia
DC Trampert, SFJ van de Graaf, A Jongejan… - Journal of …, 2021 - Elsevier
… Bicarbonate is a key component of human bile and impaired biliary bicarbonate secretion
is … Ciliated and goblet epithelial cells in the airways maintain the airway surface liquid (ASL) …
is … Ciliated and goblet epithelial cells in the airways maintain the airway surface liquid (ASL) …