… In this review, we focus on macrophage targeting, based on the results so far obtained in
preclinical models of inflammatory diseases and cancer. Pros and cons of these therapeutic …

… of the immunopathogenesis of inflammatory bowel disease (IBD) has opened new avenues
for developing targeted therapies. These advances in treatment options targeting different …

… Over the last several decades, many therapeutic strategies targeting CXCR2 have shown …
cancer and inflammatory diseases. We also discuss its potential use in targeted therapies. …

… -target side effects with only modest success in controlling inflammatory disease symptoms
[18]. … could be used as a macrophage-targeted therapy for inflammation-related diseases [69]. …

… shared targeted therapies for inflammatory diseases We identified one targeted therapy
investigated in all 10 diseases: … Two targeted therapies were assessed in 8 of the 10 diseases: …

… In this review we focus on four inflammatory cytokines—tumor … diseases. On the basis of
pre-clinical and clinical data, we specifically discuss the therapeutic rationale for targeting these …

… Importantly, such roles illustrate why therapeutic targeting of IL-6 family members has been
often associated with clinical benefit in inflammatory diseases, where these processes are …

… , is to make measures of inflammation that are more meaningful, and which can guide specific
targeted therapies. In this Review, we consider the roles of inflammatory processes in the …

… inflammatory disease models, ranging from atopic dermatitis, to acute lung injury, autoimmune
disease, … To date, the four LXR-targeted drugs that have made it to phase I clinical trials …

… as a target for therapy of inflammatory diseases. The extreme … in rheumatoid arthritis (RA)
and Crohn’s disease [1], [2], [3], [4]… guidance of TNF targeting therapy in inflammatory diseases. …