Oxidative stress in the pathogenesis of Alzheimer's disease and cerebrovascular disease with therapeutic implications

A Jurcau, A Simion - … (Formerly Current Drug Targets-CNS & …, 2020 - ingentaconnect.com
The significant gain in life expectancy led to an increase in the incidence and prevalence of
dementia. Although vascular risk factors have long and repeatedly been shown to increase …

Sirtuins: possible clinical implications in cardio and cerebrovascular diseases

V Conti, M Forte, G Corbi, G Russomanno… - Current Drug …, 2017 - ingentaconnect.com
… and non-pharmacological therapies, cardio and cerebrovascular diseases are still a …
pathways involved in cardio and cerebrovascular diseases has highlighted the presence of …

Intracranial atherosclerotic disease: mechanisms and therapeutic implications

S Yaghi, S Prabhakaran, P Khatri, DS Liebeskind - Stroke, 2019 - Am Heart Assoc
In patients with ischemic stroke, identifying the underlying mechanism has important therapeutic
implications. For instance, studies have shown that anticoagulation therapy may not be …

[HTML][HTML] APOE2: protective mechanism and therapeutic implications for Alzheimer's disease

Z Li, F Shue, N Zhao, M Shinohara, G Bu - Molecular neurodegeneration, 2020 - Springer
… exhibit increased risk of certain cerebrovascular diseases and neurological disorders. Here,
we … Finally, we discuss potential therapeutic strategies designed to leverage the protective …

[HTML][HTML] Arginine derivatives in cerebrovascular diseases: mechanisms and clinical implications

GM Grosse, E Schwedhelm, H Worthmann… - International Journal of …, 2020 - mdpi.com
cerebrovascular diseasescerebrovascular ischemic diseases. We discuss the complex
mechanisms of arginine metabolism in health and disease and its potential clinical implications

Differences in the prevention and control of cardiovascular and cerebrovascular diseases

C Liu, L Du, S Wang, L Kong, S Zhang, S Li… - Pharmacological …, 2021 - Elsevier
… , including heart coronary, brain, and peripheral vascular diseases [3], [4]. Sometimes we
also discuss CAVDs and cerebrovascular diseases (CEVDs) separately. At present, there are …

Microbiota in cerebrovascular disease: a key player and future therapeutic target

S Tonomura, M Ihara… - Journal of Cerebral Blood …, 2020 - journals.sagepub.com
… plays an essential role in cerebrovascular diseases. We introduce the … therapeutic avenues.
We suggest ways to resolve the vast inter-individual diversity of cerebrovascular disease

[HTML][HTML] Blood pressure variability and therapeutic implications in hypertension and cardiovascular diseases

C Nardin, M Rattazzi, P Pauletto - High Blood Pressure & Cardiovascular …, 2019 - Springer
… Nishioka and colleagues investigated a population of 309 patients with a history of
cerebrovascular disease and found a higher BPV associated with BBs rather than CCBs or ARBs [23]…

Cerebrovascular disease: consequences of obesity-induced endothelial dysfunction

L Letra, C Sena - Obesity and Brain Function, 2017 - Springer
… overweight and obesity in the incidence of cerebrovascular disease, many aspects of this
association … The role of cerebrovascular endothelial function and respective modulation is also …

Antithrombotic therapy for secondary prevention of atherothrombotic events in cerebrovascular disease

D Capodanno, M Alberts, DJ Angiolillo - Nature Reviews Cardiology, 2016 - nature.com
… No guideline recommendations are available for patients with cerebrovascular disease
who … in view of the time from the cerebrovascular to the coronary event and the extent of the …