Adipose tissue macrophages: implications for obesity-associated cancer

B Li, S Sun, JJ Li, JP Yuan, SR Sun, Q Wu - Military Medical Research, 2023 - Springer
… and other cells is essential for obesity-associated cancer research. … obesity-related cancer
progression mainly in tumor types with a high composition of adipose tissue (eg, breast cancer

Adipose tissue macrophages as a therapeutic target in obesity‐associated diseases

AA Herrada, A Olate‐Briones, A Rojas, C Liu… - Obesity …, 2021 - Wiley Online Library
… In conclusion, ATMs appear to play a role in linking obesity and cancer and play important
… patients suffering cancer that are also obese has the potential to prevent tumor progression. …

[HTML][HTML] Obesity and cancer: the role of adipose tissue and adipo-cytokines-induced chronic inflammation

R Divella, R De Luca, I Abbate, E Naglieri… - … of Cancer, 2016 - ncbi.nlm.nih.gov
… To date the precise mechanisms behind this obesity-cancer link is not yet … obesity and
cancer we support that inflammatory state specific of obesity may be important in obesity-cancer

Adipose tissue macrophages: going off track during obesity

L Boutens, R Stienstra - Diabetologia, 2016 - Springer
macrophages in lean and obese adipose tissue. The origin of macrophages residing in lean
and obese adipose tissue … ATMs during the development of obesity will be discussed. Finally…

Properties and functions of adipose tissue macrophages in obesity

L Russo, CN Lumeng - Immunology, 2018 - Wiley Online Library
… diseases, and certain forms of cancer] remains on the rise.1 … signaling profiles in macrophages
during obesity-induced AT … tissue macrophage (ATM) biology in the setting of obesity and …

Metabolically activated adipose tissue macrophages link obesity to triple-negative breast cancer

P Tiwari, A Blank, C Cui, KQ Schoenfelt… - Journal of Experimental …, 2019 - rupress.org
Obesity is associated with increased incidence and severity of triple-negative breast cancer
(… Here, we show that obesity reprograms mammary adipose tissue macrophages to a pro-…

Obesity and cancer: inflammation bridges the two

R Kolb, FS Sutterwala, W Zhang - Current opinion in pharmacology, 2016 - Elsevier
… in adipose tissue macrophages in obese white adipose tissue. … tissue macrophages in white
adipose tissue from obese … adipose tissue can also shift the polarization of macrophages, …

Obesity programs macrophages to support cancer progression

A Singh, SS Mayengbam, H Yaduvanshi, MR Wani… - Cancer research, 2022 - AACR
… microenvironment in obesity, adipose tissue macrophages (… of macrophages in obesity-influenced
cancer progression. … and macrophage infiltration in the breast tissue of obese women. …

Obesity and cancer mechanisms: tumor microenvironment and inflammation

NM Iyengar, A Gucalp, AJ Dannenberg… - Journal of clinical …, 2016 - ascopubs.org
obesity, which include cancer promotion. Our understanding of the mechanisms linking obesity
to cancerObesity is currently defined by an elevated body mass index (BMI), typically as …

Role of adipose tissue macrophages in obesity-related disorders

S Chakarov, C Blériot, F Ginhoux - Journal of Experimental Medicine, 2022 - rupress.org
… of the adipose tissue environment, while highlighting its heterogeneity. Finally, we detail
how obesity transforms both adipose tissue and local macrophage populations. Understanding …