[HTML][HTML] Protective Effect of Adalimumab on Diabetic Nephropathy by Regulating TNF-α Signal Pathway

Z Ding, H Jiang, Y Fan, G Sun - Iranian Journal of Public Health, 2021 - ncbi.nlm.nih.gov
… by inhibiting TNF-α signal pathway This study explored the effects of adalimumab on TNF-α
signal pathway in DN. The results showed that the content MCP-1, N F-kB TNF-α and its …

Stem Cell‐Derived Exosomes Prevent Aging‐Induced Cardiac Dysfunction through a Novel Exosome/lncRNA MALAT1/NF‐κB/TNFα Signaling Pathway

B Zhu, L Zhang, C Liang, B Liu, X Pan… - Oxidative medicine …, 2019 - Wiley Online Library
… , but the signaling molecules responsible for the inactivation of NF-κB and TNF-α remain …
in turn inhibits the NF-κB/TNF-α signaling pathway. These findings will lead to the development …

Tumor necrosis factor alpha induces neural stem cell apoptosis through activating p38 MAPK pathway

N Chen, F Wei, L Wang, S Cui, Y Wan, S Liu - Neurochemical research, 2016 - Springer
… the signaling pathways responsible for TNF-α-induced apoptosis in NSCs. TNF-α treatment
impairs … Additionally, TNF-α remarkably increased the expression of phosphatidylinositol p38 …

TNF-α regulates microglial activation via the NF-κB signaling pathway in systemic lupus erythematosus with depression

X Kong, Z Zhang, T Fu, J Ji, J Yang, Z Gu - International journal of biological …, 2019 - Elsevier
… This study aimed to investigate the effects of tumor necrosis factor-α (TNF-α) on systemic lupus
… showed that TNF-α activated microglia by upregulating the NF-κB signaling pathway and …

TNF-α pathway and T-cell immunity are activated early during the development of diabetic nephropathy in Type II Diabetes Mellitus

…, Μ Stangou, P Sarafidis, A Gouliovaki… - Clinical …, 2020 - Elsevier
… the possible involvement of TNF-α signaling pathway and T-lymphocyte activation in DN. …
The present study aimed to investigate the role of TNF-α signaling pathway and T lymphocyte …

TNF-α activates Wnt signaling pathway to promote the invasion of human colon cancer stem cells

X Wei, X Li, F Kong, L Ma, Y Sui, D Chen… - Xi bao yu fen zi Mian yi …, 2018 - europepmc.org
… of TNF-α were confirmed by MTT assay. DKK1 as an inhibitor of the Wnt signaling pathway
was … The experiment cells were divided into control group, TNF-α treatment group and TNF-α

TNF-α and IL-6: the link between immune and bone system

T Wang, C He - Current drug targets, 2020 - ingentaconnect.com
… down-regulated in BMSCs enriched from TNFα transgenic mice, because of increased
Wwp1 mediated by TNF-α- signaling pathways. Wwp1 stimulates proteosomal degradation of …

The dual role of tumor necrosis factor-alpha (TNF-α) in breast cancer: molecular insights and therapeutic approaches

D Cruceriu, O Baldasici, O Balacescu… - Cellular Oncology, 2020 - Springer
… of the p38/MAPK pro-proliferation pathway in T47D cells [63], … activities of TNF-α in relation
with the ER signaling pathway in … point between the TNF-α and ER signaling pathways, with a …

[HTML][HTML] Contribution of NOTCH signaling pathway along with TNF-α in the intestinal inflammation of ulcerative colitis

…, M Haghazali, B Khanabadi, A Meyfour - … and hepatology from …, 2019 - ncbi.nlm.nih.gov
… of NOTCH signaling pathway and TNF-α protein using SIGNOR database. TNF-α as a pro-…
-loop-helix gene and a target gene of NOTCH signaling. On the other hand, several lines of …

Pathogenetic and therapeutic applications of tumor necrosis factor-α (TNF-α) in major depressive disorder: a systematic review

K Ma, H Zhang, Z Baloch - International journal of molecular sciences, 2016 - mdpi.com
… form of the TNF homotrimer [33]. Maximum data about the TNF signaling pathway have
been … The intracellular DD are vital for starting apoptosis and other signaling pathways after …