Sensitivity of transcription factors to DNA methylation

É Héberlé, AF Bardet - Essays in biochemistry, 2019 - portlandpress.com
… Together with the observation of a strong anti-correlation between TF binding and DNA
methylation patterns genome wide, a new actively discussed hypothesis has emerged where …

Transcription factors as readers and effectors of DNA methylation

H Zhu, G Wang, J Qian - Nature Reviews Genetics, 2016 - nature.com
… in vivo, although further in vivo genome-wide characterization of TF binding patterns and
high-resolution DNA methylation analyses are needed to strengthen the evidence base. The …

Quantitative analysis of the DNA methylation sensitivity of transcription factor complexes

JF Kribelbauer, O Laptenko, S Chen, GD Martini… - Cell reports, 2017 - cell.com
… of transcription factor binding to DNA modification in vitro using massively parallel sequencing.
Feature-based modeling quantifies the effect of cytosine methylation … modification pattern

[HTML][HTML] Toward a mechanistic understanding of DNA methylation readout by transcription factors

JF Kribelbauer, XJ Lu, R Rohs, RS Mann… - Journal of molecular …, 2020 - Elsevier
… , aberrant DNA methylation patterns play a … DNA methylation is transitioning between,
rather than maintaining cellular states. This line of thinking raises the question how methylation

Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patterns

MK Kirby, RC Ramaker, BS Roberts, BN Lasseigne… - BMC cancer, 2017 - Springer
DNA methylation patterns are greatly altered in prostate … We have discovered patterns of
DNA methylation marks that … transcription factors binding in these differentially methylated

DNA methylation events in transcription factors and gene expression changes in colon cancer

A Diez-Villanueva, R Sanz-Pamplona… - …, 2020 - Taylor & Francis
… Moreover, we have not found differences in global methylation patterns between normal
adjacent mucosa (N) and colon tissues from healthy donors (M). We previously reported a …

PGC7 promotes tumor oncogenic dedifferentiation through remodeling DNA methylation pattern for key developmental transcription factors

Q Yan, Y Zhang, X Fang, B Liu, TL Wong… - Cell Death & …, 2021 - nature.com
… been reported to preserve DNA methylation pattern in either hyper- … DNA methylation.
Whole-genome bisulfite genomic sequencing (WGBS) was performed to compare the methylation

Pan-cancer predictions of transcription factors mediating aberrant DNA methylation

D Detilleux, YG Spill, D Balaramane, M Weber… - Epigenetics & …, 2022 - Springer
… predict transcription factors that lead to hyper-methylated regions upon transcription factor
loss … Last we tested the consequence of TF binding on DNA methylation patterns by deleting …

MethMotif. Org 2024: a database integrating context-specific transcription factor-binding motifs with DNA methylation patterns

M Dyer, QXX Lin, S Shapoval, D Thieffry… - Nucleic Acids …, 2024 - academic.oup.com
… Given these unique DNA methylation patterns in plants, distinct from other taxonomic groups,
… to differentiate between symmetrical/asymmetrical or strand-specific methylation (Figure 3). …

Variation of DNA methylation patterns associated with gene expression in rice (Oryza sativa) exposed to cadmium

SJ Feng, XS Liu, H Tao, SK Tan, SS Chu… - Plant, Cell & …, 2016 - Wiley Online Library
… , metal transport and transcription factors. Most of the DNA methylation-modified genes were
… A subset of loss of function mutants defective in DNA methylation and histone modification …