Performance of an ultra-sensitive Plasmodium falciparum HRP2-based rapid diagnostic test with recombinant HRP2, culture parasites, and archived whole blood …

S Das, RB Peck, R Barney, IK Jang, M Kahn, M Zhu… - Malaria journal, 2018 - Springer
… assess uRDT performance in endemic areas. Recently, the … a low transmission area with
parasitaemia and HRP2 ranging … a high transmission area with parasitaemia and HRP2 ranging …

HRP2 and HRP3 cross-reactivity and implications for HRP2-based RDT use in regions with Plasmodium falciparum hrp2 gene deletions

A Kong, SA Wilson, Y Ah, D Nace, E Rogier, M Aidoo - Malaria Journal, 2021 - Springer
… -conjugated beads), a density often associated with asymptomatic infection in high transmission
settings, HRP2 bands on all three RDTs were positive, although at low band intensities (…

Evaluation of an ultrasensitive HRP2–based rapid diagnostic test for detection of asymptomatic Plasmodium falciparum parasitaemia among children in western …

LB Turnbull, G Ayodo, V Knight, CC John, MS McHenry… - Malaria Journal, 2022 - Springer
… is lower than we report for symptomatic adults in low- transmission areas [17], this difference
in performance may be related to the lower level of malaria exposure and immunity in the …

False-negative malaria rapid diagnostic tests in Rwanda: impact of Plasmodium falciparum isolates lacking hrp2 and declining malaria transmission

CT Kozycki, N Umulisa, S Rulisa, EI Mwikarago… - Malaria journal, 2017 - Springer
… the sensitivity of HRP2 RDTs at 3 sites with varying intensities of transmission in Rwanda to
HRP2 RDT after a fall in malaria transmission. In Rukara, monthly estimates of HRP2 RDT

Factors affecting the performance of HRP2-based malaria rapid diagnostic tests

X Martiáñez-Vendrell, M Skjefte, R Sikka… - Tropical Medicine and …, 2022 - mdpi.com
… of type 2 repeats and poor HRP2 RDT diagnosis (p = 0.046). … non-sensitive to HRP2 RDTs
based on HRP2 sequence for the … performance of RDTs in areas of low malaria transmission […

Prevalence and clinical impact of malaria infections detected with a highly sensitive HRP2 rapid diagnostic test in Beninese pregnant women

V Briand, G Cottrell, N Tuike Ndam… - Malaria journal, 2020 - Springer
… In conclusion, these results are complementary to those previously reported in a low malaria
transmission area. They confirm the higher overall performance of uRDT, compared to the …

Ultra-sensitive RDT performance and antigen dynamics in a high-transmission Plasmodium falciparum setting in Mali

EN Reichert, JCC Hume, I Sagara, SA Healy… - Malaria Journal, 2020 - Springer
… -sensitive HRP2-based Alere™ Malaria Ag Pf RDT (uRDT). The samples were collected
as part of a transmission-blocking vaccine trial in a high transmission region for Plasmodium …

Diagnosing congenital malaria in a high-transmission setting: clinical relevance and usefulness of P. falciparum HRP2-based testing

HM Natama, DF Ouedraogo, H Sorgho… - Scientific reports, 2017 - nature.com
… a HRP2 RDT in plasma and LM to detect Plasmodium falciparum infections in cord blood
samples. In addition, we used an Enzyme-linked Immunosorbent Assay (ELISA) kit to examine …

… of rapid diagnostic tests in malaria surveys in areas with varied transmission intensity in Uganda 2017-2019: Implications for selection and use of HRP2 RDTs

AB Bosco, JI Nankabirwa, A Yeka, S Nsobya, K Gresty… - PloS one, 2020 - journals.plos.org
… between the HRP2 RDT and PCR assay results in the (RDT+/microscopy+) and (RDT-/…
Factors associated with false-negative RDT results in the (RDT-/microscopy+) samples …

Diagnostic performance of an ultrasensitive HRP2-based malaria rapid diagnostic test kit used in surveys of afebrile people living in Southern Ghana

FK Acquah, D Donu, EK Obboh, D Bredu, B Mawuli… - Malaria Journal, 2021 - Springer
… Differences of 20% -40% have been observed in a high transmission setting of Uganda
and a low transmission setting of Myanmar respectively [35]. The slight difference in specificity …