Impact of tumor microenvironment composition on therapeutic responses and clinical outcomes in cancer

F Anari, C Ramamurthy, M Zibelman - Future Oncology, 2018 - Taylor & Francis
therapy had response rate of 18.56%. However, this study showed no OS advantage of any
one regimen. … -2 produced durable objective responses in patients with metastatic melanoma …

Association between changes in body composition and neoadjuvant treatment for pancreatic cancer

M Sandini, M Patiňo, CR Ferrone… - JAMA …, 2018 - jamanetwork.com
… Because NT is becoming the standard of care for patients with BRPC … composition and
clinical response. In this context, it may be proposed that screening changes in body composition

[HTML][HTML] Survivorship in immune therapy: assessing toxicities, body composition and health-related quality of life among long-term survivors treated with antibodies to …

JR Patrinely Jr, AC Young, H Quach… - European journal of …, 2020 - Elsevier
… Herein, we have assessed a large cohort of patients treated with anti–PD-1/PD-L1 to identify
the long-term immune toxicities, health outcomes, body composition metrics and health-…

Development of new tuberculosis drugs: translation to regimen composition for drug-sensitive and multidrug-resistant tuberculosis

JP Ernest, N Strydom, Q Wang, N Zhang… - Annual review of …, 2021 - annualreviews.org
… (➅) Resistance models incorporate mechanisms related to the emergence of resistance to
therapy over time. (➆) Biomarkers of disease progression and treatment response in different …

Relevance of tumor-infiltrating immune cell composition and functionality for disease outcome in breast cancer

RD Bense, C Sotiriou… - Journal of the …, 2017 - academic.oup.com
… all patients benefit from standard treatment regimens (1,2), resulting in undertreatment or
overtreatment in many women. Predicting treatment response is … For the treatment regimen, we …

[HTML][HTML] Value of pyrazinamide for composition of new treatment regimens for multidrug-resistant Mycobacterium tuberculosis in China

H Xia, S van Den Hof, F Cobelens, Y Zhou… - BMC Infectious …, 2020 - Springer
… Before a new RR/MDR treatment regimen composed of bedaquiline and linezolid can be …
drug in the treatment regimen of RR/MDR-TB given that such a regimen is widely accessible …

The efficacy of direct anti-HCV drugs improves early post-liver transplant survival and induces significant changes in waiting list composition

G Crespo, N Trota, MC Londoño, E Mauro… - Journal of …, 2018 - Elsevier
… cannot be fully discarded, it must be stressed that the use of these regimens was extremely
limited in our cohort, and thus their contribution in the changes in the waiting list or post-LT …

[HTML][HTML] The impact of body composition parameters on ipilimumab toxicity and survival in patients with metastatic melanoma

LE Daly, DG Power, Á O'Reilly, P Donnellan… - British journal of …, 2017 - nature.com
… toxicity to ipilimumab in patients with metastatic melanoma. A … in body composition that occur
during treatment and to assess … -treatment CT images taken as part of routine patient care

Drug resistance in non-small cell lung Cancer (NSCLC): Impact of genetic and non-genetic alterations on therapeutic regimen and responsiveness

M Terlizzi, C Colarusso, A Pinto, R Sorrentino - Pharmacology & …, 2019 - Elsevier
… a de novo lack of treatment response, whereas acquired … mutated NSCLC patients who
achieve an effective response or … while they are still on the targeted therapy (Jackman et al., 2010)…

Principles for constructing a tuberculosis treatment regimen: the role and definition of core and companion drugs

A Van Deun, T Decroo, A Piubello… - … of Tuberculosis and …, 2018 - ingentaconnect.com
treatment regimenscomposition of treatment regimens for MDR-TB. We propose to reserve
the term ‘core drug’ for the one drug in a regimen that contributes most to relapse-free cure. …