… therapy of the dual epidermal growth factor … tumor in phase II clinical trial (NCT00326495).
Secondly, aberrant expression of VEGFR and genetic alteration of fibroblast growth factor …

… Since then, several other growth factors and their receptors have been disclosed and …
The solid tumor of human has significant level of growth factor receptors. The growth factor …

… secrete growth factors, cytokines and extracellular matrix proteins which promote growth, …
Fibroblasts are the predominant constituent of the tumor stroma and Hepatocyte Growth Factor (…

… growth factor-β receptor-2 (TβRII) with high affinity. This binding requires the participation
of the transforming growth factor-β … Targeted tumor therapy with the TGF-beta 2 antisense …

… The TF/factor VIIa complex enhances tumor growth by activating protease-activated … of
angiogenic factors, such as vascular endothelial growth factor. AsTF increases tumor growth by …

… Placenta growth factor (PlGF) and VEGFB bind selectively to VEGF receptor 1 (VEGFR1), …
certain growth factors such as hepatocyte growth factor and connective tissue growth factor, …

… of oxygen, nutrients, and growth factors as well as tumor dissemination to distant organs. …
solid tumors that depend on cutting or at least reducing the blood supply to tumor micro-…

… Vascular endothelial growth factor (VEGF) is a key mediator of tumor angiogenesis … factor
and its receptor [29]. TAMs induce various growth factors such as basic fibroblast growth factor, …

… in the anti-tumor immune response. In addition, we summarize therapeutic strategies based
… cleave the extracellular matrix and release heparin bound growth factor such as VEGF-A [38]…

… growth factor (VEGF). VEGF-mediated signaling has quickly become one of the most
promising anti-angiogenic therapeutic … is severely limited in certain tumor types or shows only …