[HTML][HTML] Regulation of ZEB1 function and molecular associations in tumor progression and metastasis

M Perez-Oquendo, DL Gibbons - Cancers, 2022 - mdpi.com
… of ZEB1 in mediating tumor progression and metastasis and describe the ways in which protein
modifications can regulate its molecular associations and function… regulation of ZEB1′s …

[HTML][HTML] The roles of ZEB1 in tumorigenic progression and epigenetic modifications

Y Zhang, L Xu, A Li, X Han - Biomedicine & Pharmacotherapy, 2019 - Elsevier
ZEB1ZEB1 and these chromatin-modifying enzymes may represent an efficient for treating
cancer. In this review, we outlined the biological function of ZEB1 in tumorigenic progression

Pleiotropic roles for ZEB1 in cancer

J Caramel, M Ligier, A Puisieux - Cancer research, 2018 - AACR
ZEB1 is a prime element of a network of transcription factors … Aberrant expression of ZEB1
has been reported in a variety … unsuspected intrinsic oncogenic functions of ZEB1 that impact …

[HTML][HTML] The curious case of ZEB1

M Madany, T Thomas, LA Edwards - Discoveries, 2018 - ncbi.nlm.nih.gov
… In vivo studies 38 have shown that tumors with increased ZEB1 and lowered E-Cadherin …
cementing the role of ZEB1 in EMT and tumor progression. This role of ZEB1 has been further …

[HTML][HTML] Inactivation of endothelial ZEB1 impedes tumor progression and sensitizes tumors to conventional therapies

R Fu, Y Li, N Jiang, BX Ren, CZ Zang… - The Journal of …, 2020 - Am Soc Clin Investig
… of vascular ZEB1 in tumor progression, we evaluated LLC and B16F10 tumor models by
subcutaneous implantation of LLC and B16F10 cells into 9-week-old Zeb1 WT and Zeb1 iΔEC …

Tumor‐associated macrophages (TAMs) depend on ZEB1 for their cancer‐promoting roles

M Cortés, L Sanchez‐Moral, O de Barrios… - The EMBO …, 2017 - embopress.org
… We then turned to investigate the molecular mechanisms by which the expression of ZEB1
in TAMs promotes an enhanced tumor progression in the ID8 cancer model. The CCL2-CCR2 …

ZEB1: New advances in fibrosis and cancer

L Cheng, MY Zhou, YJ Gu, L Chen, Y Wang - Molecular and Cellular …, 2021 - Springer
… structure of ZEB1 and the protein binding sites of ZEB1 with some … roles of ZEB1 in fibrosis
and cancer progression to elaborate … , ZEB1 facilitates tumor progression and promotes tumor

[HTML][HTML] Oncogenic functions of the EMT-related transcription factor ZEB1 in breast cancer

HT Wu, HT Zhong, GW Li, JX Shen, QQ Ye… - Journal of translational …, 2020 - Springer
… Therefore, further investigations to reveal the contribution of various tumor
microenvironmental factors to tumor progression will lead to a comprehensive understanding of …

[HTML][HTML] Prognostic value of ZEB-1 in solid tumors: a meta-analysis

B Chen, B Chen, Z Zhu, W Ye, J Zeng, G Liu, S Wang… - BMC cancer, 2019 - Springer
… The inclusion criteria were as follows: (1) diagnosis of human solid tumor; (2) the role of
ZEB-1 in the tumor progression must be investigated; (3) description of the relevance of …

Zeb1 induces immune checkpoints to form an immunosuppressive envelope around invading cancer cells

Y Guo, X Lu, Y Chen, B Rendon, RA Mitchell… - Science …, 2021 - science.org
Zeb1-AD cells, Zeb1 lo AC cells in the central tumor in TGFb1-deficient regions, and clusters
of Zeb1 hi invading AC cells at the tumorZeb1, PDL1, and CD47 during tumor progression; …