… According to the concept of phenotype switching, tumor progression does not necessarily
rely on clonal evolution but rather on the reversible reprogramming of signaling networks in …

… ABCB5 regulates the expression level of ZEB1. (A) Clustering … between ABCB5 and ZEB1,
we assessed ZEB1 levels in the … 6A and B), the expression level of ZEB1 was significantly …

… mechanism to drive tumor progression in CRC: MeCP2 binds to SPI1 and aids its recruitment
to the ZEB1 promoter, which in turn, affects ZEB1 expression at the transcription level. …

… ZEB1 functions as a critical regulator of TGF-β–mediated EMT by recruiting co-activators and
co-repressors [5,6], and plays important roles in ESCC progression [… and tumor progression …

… microenvironment (TME) may induce, through mutagenic or epigenetic alterations, a CSC
expansion that potentiates tumor progression 2 . Notably, CSCs are not uniformly distributed …

… tumors with Zeb1+ tumor cells and with stroma rich in Zeb1+ cells, and since TNBCs have
been reported to have higher rates of the ‘hot’/‘inflamed’ tumors … relationship between Zeb1-…

… a transcriptional complex within ZEB1 promotor, thereby facilitating the ZEB1 expression. …
with ZEB1 expression in this study. To gain more insights into CPEB4-mediated ZEB1 of GC …

… functional disruption of Zeb1–Ctbp complex by the ZEB1 inhibitors is realized through both
the translocation of Zeb1 to … genes, and the attenuation of Zeb1 that results in the inhibition of …

… crucial roles in tumor progression and may be a useful maker for OC prognosis. … ZEB1 is
directly targeted by miR-454 such that its overexpression suppresses the expression of ZEB1, …

… tumor progression, it was not known whether Zeb1 influences NHE1 expression. We found
that shRNA depletion of Zeb1 … S4), suggesting that Zeb1 may regulate NHE1 expression at …