Zebrafish embryos as a screen for DNA methylation modifications after compound exposure

MC Bouwmeester, S Ruiter, T Lommelaars… - Toxicology and applied …, 2016 - Elsevier
… In this study, we examined the applicability of the zebrafish embryo as a screening model
for DNA methylation modifications. Embryos were exposed from 0 to 72 h post fertilization (hpf) …

DNA methylation and gene expression alterations in zebrafish embryos exposed to cadmium

X Bian, Y Gao - Environmental Science and Pollution Research, 2021 - Springer
… mechanism of DNA methylation in zebrafish embryo under … DNA methylation level of
zebrafish embryo, and we observed global methylation and signaling pathway-related gene DNA

[HTML][HTML] Associations between behavioral effects of bisphenol A and DNA methylation in zebrafish embryos

PA Olsvik, P Whatmore, SJ Penglase… - Frontiers in …, 2019 - frontiersin.org
… affect global DNA methylation, but 20,474 differentially methylated (DM) sites in … zebrafish
embryo swimming activity at very low concentrations as well as affecting numerous methylated

Loss of DNA methylation in zebrafish embryos activates retrotransposons to trigger antiviral signaling

Y Chernyavskaya, R Mudbhary, C Zhang… - …, 2017 - journals.biologists.com
… in zebrafish mutants that lack DNA methylation due to uhrf1 (Sadler et al., 2007) or dnmt1
(Anderson et al., 2009) mutations. Although DNA methylation … regulated by DNA methylation (…

[HTML][HTML] DNA methyltransferases and stress-related genes expression in zebrafish larvae after exposure to heat and copper during reprogramming of DNA methylation

J Dorts, E Falisse, E Schoofs, E Flamion… - Scientific reports, 2016 - nature.com
… To conclude, our study is the first to report that the DNA methylation reprogramming is
sensitive to the effects of environmental stressors in zebrafish embryos. As a matter of fact, we …

[HTML][HTML] Fipronil-induced enantioselective developmental toxicity to zebrafish embryo-larvae involves changes in DNA methylation

Y Qian, C Wang, J Wang, X Zhang, Z Zhou, M Zhao… - Scientific Reports, 2017 - nature.com
… a well-established genome-wide DNA methylation analysis strategy to determine the role
of DNA methylation during developmental disorders of zebrafish embryo-larvae caused by the …

PM2. 5-induced extensive DNA methylation changes in the heart of zebrafish embryos and the protective effect of folic acid

Y Jiang, J Li, F Ren, C Ji, S Aniagu, T Chen - Environmental Pollution, 2019 - Elsevier
DNA methylation changes could be diminished by FA supplementation. In this study, zebrafish
embryos … Genomic-wide DNA methylation analysis identified both DNA hypo- and hyper-…

[HTML][HTML] A DNA methylation age predictor for zebrafish

B Mayne, D Korbie, L Kenchington, B Ezzy… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
… However, it is unknown if DNA methylation is predictive of age during post-embryonic … we
identify DNA methylation biomarkers that accurately predict the age of zebrafish from caudal fin …

DNA methylation and gene expression alterations in zebrafish early-life stages exposed to the antibacterial agent triclosan

E Falisse, B Ducos, PA Stockwell, IM Morison… - Environmental …, 2018 - Elsevier
… , particularly during embryogenesis when DNA methylation patterns are being established.
… on DNA methylation and its correlation with gene expression, zebrafish embryos were …

Embryonic exposure to benzo (a) pyrene inhibits reproductive capability in adult female zebrafish and correlation with DNA methylation

D Gao, J Lin, K Ou, Y Chen, H Li, Q Dai, Z Yu… - Environmental …, 2018 - Elsevier
… hatching success of F1 embryos (Booc et al., 2014). BaP exposure to zebrafish embryos
decreased the global methylation, suggesting that aberrant DNA methylation can relate with BaP…