[HTML][HTML] Feasibility of a pragmatic PBPK modeling approach: towards model-informed dosing in pediatric clinical care
JEM van der Heijden, JJM Freriksen… - Clinical …, 2022 - Springer
Abstract Background and Objective More than half of all drugs are still prescribed off-label to
children. Pharmacokinetic (PK) data are needed to support off-label dosing, however for …
children. Pharmacokinetic (PK) data are needed to support off-label dosing, however for …
Feasibility of a Pragmatic PBPK Modeling Approach: Towards Model-Informed Dosing in Pediatric Clinical Care.
JEM van der Heijden, JJM Freriksen… - Clinical …, 2022 - europepmc.org
Methods Seven drugs, with various PK characteristics, were selected (meropenem,
ceftazidime, azithromycin, propofol, midazolam, lorazepam, and caffeine) as a proof of …
ceftazidime, azithromycin, propofol, midazolam, lorazepam, and caffeine) as a proof of …
Feasibility of a Pragmatic PBPK Modeling Approach: Towards Model-Informed Dosing in Pediatric Clinical Care.
JEM van der Heijden, JJM Freriksen… - Clinical …, 2022 - search.ebscohost.com
Abstract Background and Objective: More than half of all drugs are still prescribed off-label
to children. Pharmacokinetic (PK) data are needed to support off-label dosing, however for …
to children. Pharmacokinetic (PK) data are needed to support off-label dosing, however for …
[PDF][PDF] Feasibility of a Pragmatic PBPK Modeling Approach: Towards Model-Informed Dosing in Pediatric Clinical Care
JEM van der Heijden, JJM Freriksen… - 2022 - repository.ubn.ru.nl
BACKGROUND AND OBJECTIVE: More than half of all drugs are still prescribed off-label to
children. Pharmacokinetic (PK) data are needed to support off-label dosing, however for …
children. Pharmacokinetic (PK) data are needed to support off-label dosing, however for …
[HTML][HTML] Feasibility of a Pragmatic PBPK Modeling Approach: Towards Model-Informed Dosing in Pediatric Clinical Care
JEM van der Heijden, JJM Freriksen… - Clinical …, 2022 - ncbi.nlm.nih.gov
Methods Seven drugs, with various PK characteristics, were selected (meropenem,
ceftazidime, azithromycin, propofol, midazolam, lorazepam, and caffeine) as a proof of …
ceftazidime, azithromycin, propofol, midazolam, lorazepam, and caffeine) as a proof of …
Feasibility of a Pragmatic PBPK Modeling Approach: Towards Model-Informed Dosing in Pediatric Clinical Care
JEM van der Heijden, JJM Freriksen… - Clinical …, 2022 - pubmed.ncbi.nlm.nih.gov
Background and objective More than half of all drugs are still prescribed off-label to children.
Pharmacokinetic (PK) data are needed to support off-label dosing, however for many drugs …
Pharmacokinetic (PK) data are needed to support off-label dosing, however for many drugs …
[PDF][PDF] Feasibility of a Pragmatic PBPK Modeling Approach: Towards Model‑Informed Dosing in Pediatric Clinical Care
JEM van der Heijden, JJM Freriksen… - 2022 - pure.eur.nl
Abstract Background and Objective More than half of all drugs are still prescribed off-label to
children. Pharmacokinetic (PK) data are needed to support off-label dosing, however for …
children. Pharmacokinetic (PK) data are needed to support off-label dosing, however for …
Feasibility of a Pragmatic PBPK Modeling Approach: Towards Model-Informed Dosing in Pediatric Clinical Care
JEM van der Heljden, JJM Freriksen… - Clinical …, 2022 - search.proquest.com
Abstract Background and Objective More than half of all drugs are still prescribed off-label to
children. Pharmacokinetic (PK) data are needed to support off-label dosing, however for …
children. Pharmacokinetic (PK) data are needed to support off-label dosing, however for …
[PDF][PDF] Feasibility of a Pragmatic PBPK Modeling Approach: Towards Model‑Informed Dosing in Pediatric Clinical Care
JEM van der Heijden, JJM Freriksen… - 2022 - pure.eur.nl
Abstract Background and Objective More than half of all drugs are still prescribed off-label to
children. Pharmacokinetic (PK) data are needed to support off-label dosing, however for …
children. Pharmacokinetic (PK) data are needed to support off-label dosing, however for …