Vertical Inhibition of the RAF–MEK–ERK Cascade Induces Myogenic Differentiation, Apoptosis, and Tumor Regression in H/NRASQ61X Mutant …

N Garcia, V Del Pozo, ME Yohe, CM Goodwin… - Molecular cancer …, 2022 - AACR
Oncogenic RAS signaling is an attractive target for fusion-negative rhabdomyosarcoma (FN-
RMS). Our study validates the role of the ERK MAPK effector pathway in mediating RAS …

[HTML][HTML] Vertical Inhibition of the RAF-MEK-ERK Cascade Induces Myogenic Differentiation, Apoptosis and Tumor Regression in H/NRAS Q61X-mutant …

N Garcia, V Del Pozo, ME Yohe… - Molecular cancer …, 2022 - ncbi.nlm.nih.gov
Oncogenic RAS signaling is an attractive target for fusion-negative rhabdomyosarcoma (FN-
RMS). Our study validates the role of the ERK MAPK effector pathway in mediating RAS …

[PDF][PDF] Vertical Inhibition of the RAF–MEK–ERK Cascade Induces Myogenic Differentiation, Apoptosis, and Tumor Regression in H/NRASQ61X Mutant …

N Garcia, V Del Pozo, ME Yohe, CM Goodwin… - Mol Cancer …, 2022 - sites.duke.edu
MEK or ERK inhibition. Concurrent CRAF suppression and MEK or ERK inhibition, or
concurrent pan-RAF and MEK/ERK inhibition (pan-RAFi þ MEKi/ERKi), or concurrent MEK …

Vertical Inhibition of the RAF-MEK-ERK Cascade Induces Myogenic Differentiation, Apoptosis, and Tumor Regression in H/NRASQ61X Mutant Rhabdomyosarcoma

N Garcia, V Del Pozo, ME Yohe… - Molecular cancer …, 2022 - pubmed.ncbi.nlm.nih.gov
Oncogenic RAS signaling is an attractive target for fusion-negative rhabdomyosarcoma (FN-
RMS). Our study validates the role of the ERK MAPK effector pathway in mediating RAS …

Vertical Inhibition of the RAF-MEK-ERK Cascade Induces Myogenic Differentiation, Apoptosis, and Tumor Regression in H/NRASQ61X Mutant Rhabdomyosarcoma.

N Garcia, V Del Pozo, ME Yohe… - Molecular Cancer …, 2021 - europepmc.org
Oncogenic RAS signaling is an attractive target for fusion-negative rhabdomyosarcoma (FN-
RMS). Our study validates the role of the ERK MAPK effector pathway in mediating RAS …

Vertical Inhibition of the RAF–MEK–ERK Cascade Induces Myogenic Differentiation, Apoptosis, and Tumor Regression in H/NRASQ61X Mutant Rhabdomyosarcoma

N Garcia, V Del Pozo, ME Yohe… - Molecular cancer …, 2022 - scholars.uthscsa.edu
Oncogenic RAS signaling is an attractive target for fusion-negative rhabdomyosarcoma (FN-
RMS). Our study validates the role of the ERK MAPK effector pathway in mediating RAS …