Histamine H4 receptor stimulation in the locus coeruleus attenuates neuropathic pain by promoting the coeruleospinal noradrenergic inhibitory pathway

MD Sanna, V Borgonetti, E Masini, N Galeotti - European Journal of …, 2020 - Elsevier
The locus coeruleus (LC) adrenergic nuclei constitute a pain-control inhibitory system
nucleus implicated in descending modulation of pain through the action on spinal α 2 …

Histamine H4 receptor stimulation in the locus coeruleus attenuates neuropathic pain by promoting the coeruleospinal noradrenergic inhibitory pathway

MD Sanna, V Borgonetti, E Masini… - European journal of …, 2020 - pubmed.ncbi.nlm.nih.gov
The locus coeruleus (LC) adrenergic nuclei constitute a pain-control inhibitory system
nucleus implicated in descending modulation of pain through the action on spinal α 2 …

Histamine H4 receptor stimulation in the locus coeruleus attenuates neuropathic pain by promoting the coeruleospinal noradrenergic inhibitory pathway

MD Sanna, V Borgonetti, E Masini… - EUROPEAN JOURNAL …, 2020 - flore.unifi.it
descending modulation of pain through the action on spinal α2-adrenoceptors.
Histaminergic innervation from the tuberomammillary nucleus of the LC increases firing of …