Apoptosis as a mechanism for the treatment of adult T cell leukemia: Promising drugs from benchside to bedside

M Houssein, M Khalil, M Fatfat, H Gali-Muhtasib - Drug Discovery Today, 2020 - Elsevier
Highlights•Available therapies fail to treat or eradicate adult T-cell leukemia (ATL).•HTLV-1
infection causes deregulation in apoptotic and proliferative pathways.•Preclinical drugs …

Apoptosis as a mechanism for the treatment of adult T cell leukemia: promising drugs from benchside to bedside

M Houssein, M Khalil, M Fatfat… - Drug discovery …, 2020 - pubmed.ncbi.nlm.nih.gov
Human T cell lymphotropic virus-1 (HTLV-1) is the causative agent of adult T cell leukemia
(ATL), an aggressive malignancy of mature activated T cells. Although many therapeutic …

Apoptosis as a mechanism for the treatment of adult T cell leukemia: promising drugs from benchside to bedside.

M Houssein, M Khalil, M Fatfat… - Drug Discovery …, 2020 - europepmc.org
Human T cell lymphotropic virus-1 (HTLV-1) is the causative agent of adult T cell leukemia
(ATL), an aggressive malignancy of mature activated T cells. Although many therapeutic …