Probing human heart TCA cycle metabolism and response to glucose load using hyperpolarized [2‐13C]pyruvate MRS

HY Chen, JW Gordon, N Dwork, BT Chung… - NMR in …, 2024 - Wiley Online Library
Introduction The healthy heart has remarkable metabolic flexibility that permits rapid
switching between mitochondrial glucose oxidation and fatty acid oxidation to generate ATP …

Probing Human Heart TCA Cycle Metabolism and Response to Glucose Load using Hyperpolarized [2- 13 C]Pyruvate MR Spectroscopy.

HY Chen, JW Gordon, N Dwork, BT Chung… - Medrxiv: the Preprint …, 2023 - europepmc.org
Methods Good Manufacturing Practice [2-13 C] pyruvic acid was polarized in a 5T polarizer
for 2.5-3 hours. Following dissolution, QC parameters of HP pyruvate met all safety and …

[HTML][HTML] Probing Human Heart TCA Cycle Metabolism and Response to Glucose Load using Hyperpolarized [2-13C] Pyruvate MR Spectroscopy

HY Chen, JW Gordon, N Dwork, BT Chung, A Riselli… - medRxiv - ncbi.nlm.nih.gov
Methods: Good Manufacturing Practice [2-13 C] pyruvic acid was polarized in a 5T polarizer
for 2.5–3 hours. Following dissolution, QC parameters of HP pyruvate met all safety and …

Probing Human Heart TCA Cycle Metabolism and Response to Glucose Load using Hyperpolarized [2-13C]Pyruvate MR Spectroscopy

HY Chen, JW Gordon, N Dwork, BT Chung, A Riselli… - medRxiv, 2023 - medrxiv.org
Introduction The normal heart has remarkable metabolic flexibility that permits rapid
switching between mitochondrial glucose oxidation and fatty acid (FA) oxidation to generate …

Probing Human Heart TCA Cycle Metabolism and Response to Glucose Load using Hyperpolarized [2-13C] Pyruvate MR Spectroscopy

HY Chen, JW Gordon, N Dwork… - … : the preprint server …, 2023 - pubmed.ncbi.nlm.nih.gov
Introduction The normal heart has remarkable metabolic flexibility that permits rapid
switching between mitochondrial glucose oxidation and fatty acid (FA) oxidation to generate …

Probing Human Heart TCA Cycle Metabolism and Response to Glucose Load using Hyperpolarized [2-13C] Pyruvate MR Spectroscopy

H Chen, JW Gordon, N Dwork, B Chung, A Riselli… - 2023 - europepmc.org
Methods: Good Manufacturing Practice [2-13C] pyruvic acid was polarized in a 5T polarizer
for 2.5-3 hours. Following dissolution, QC parameters of HP pyruvate met all safety and …

Probing human heart TCA cycle metabolism and response to glucose load using hyperpolarized [2-13 C] pyruvate MRS

HY Chen, JW Gordon, N Dwork, BT Chung… - NMR in … - pubmed.ncbi.nlm.nih.gov
Introduction The healthy heart has remarkable metabolic flexibility that permits rapid
switching between mitochondrial glucose oxidation and fatty acid oxidation to generate ATP …