[HTML][HTML] Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive …

K Recourt, P de Boer, P van der Ark, H Benes… - Translational …, 2023 - nature.com
JNJ-54175446 is a selective purine P2X7 receptor (P2X7R) antagonist that attenuates
microglial IL-1β/IL-18 release. In healthy volunteers, JNJ-54175446 suppressed peripheral …

Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder.

K Recourt, P de Boer, P van der Ark, H Benes… - Translational …, 2023 - europepmc.org
JNJ-54175446 is a selective purine P2X7 receptor (P2X7R) antagonist that attenuates
microglial IL-1β/IL-18 release. In healthy volunteers, JNJ-54175446 suppressed peripheral …

[HTML][HTML] Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive …

K Recourt, P de Boer, P van der Ark… - Translational …, 2023 - ncbi.nlm.nih.gov
JNJ-54175446 is a selective purine P2X7 receptor (P2X7R) antagonist that attenuates
microglial IL-1β/IL-18 release. In healthy volunteers, JNJ-54175446 suppressed peripheral …

Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder.

K Recourt, P de Boer, P van der Ark… - Translational …, 2023 - search.ebscohost.com
JNJ-54175446 is a selective purine P2X7 receptor (P2X7R) antagonist that attenuates
microglial IL-1β/IL-18 release. In healthy volunteers, JNJ-54175446 suppressed peripheral …

Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder

K Recourt, P de Boer, P van der Ark… - Translational …, 2023 - search.proquest.com
JNJ-54175446 is a selective purine P2X7 receptor (P2X7R) antagonist that attenuates
microglial IL-1β/IL-18 release. In healthy volunteers, JNJ-54175446 suppressed peripheral …

Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder

K Recourt, P de Boer, P van der Ark… - Translational …, 2023 - pubmed.ncbi.nlm.nih.gov
JNJ-54175446 is a selective purine P2X7 receptor (P2X7R) antagonist that attenuates
microglial IL-1β/IL-18 release. In healthy volunteers, JNJ-54175446 suppressed peripheral …

Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder

K Recourt, P Boer, P Ark… - Translational …, 2023 - scholarlypublications …
JNJ-54175446 is a selective purine P2X7 receptor (P2X7R) antagonist that attenuates
microglial IL-1 & beta;/IL-18 release. In healthy volunteers, JNJ-54175446 suppressed …

[引用][C] Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive …

K Recourt, P de Boer, P van der Ark, H Benes… - depression, 2023 - europepmc.org
The purine P2X7 receptor (P2X7R) is one of seven identified subtypes of adenosine
triphosphate (ATP)-gated P2X ion channels present on various human cell types. The …