E3 Ubiquitin Ligases as Molecular Machines and Platforms for Drug Development

RM Ioris, K Ferris, V D'Angiolella - Inducing Targeted Protein …, 2023 - Wiley Online Library
Many essential biological processes are regulated through protein–protein interactions.
Some natural and synthetic small‐molecule compounds also operate through induced …
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E3 Ubiquitin Ligases as Molecular Machines and Platforms for Drug Development

RM Ioris, K Ferris, V D'Angiolella - Inducing Targeted Protein …, 2022 - books.google.com
Ubiquitylation entails a cascade of enzymatic reactions where multiples of ubiquitin
molecules are covalently attached to a target protein. Polyubiquitylation of proteins acts as a …

E3 Ubiquitin Ligases as Molecular Machines and Platforms for Drug Development

RM Ioris, K Ferris, V D'Angiolella - Inducing Targeted Protein …, 2022 - books.google.com
Ubiquitylation entails a cascade of enzymatic reactions where multiples of ubiquitin
molecules are covalently attached to a target protein. Polyubiquitylation of proteins acts as a …