[HTML][HTML] A unique feature of swine ANP32A provides susceptibility to avian influenza virus infection in pigs

H Zhang, H Li, W Wang, Y Wang, GZ Han… - PLoS …, 2020 - journals.plos.org
… The permissive mechanism that allows pig cells to be infected with avian influenza virus is …
pig cellular protein ANP32A has a unique 106V/156S signature, different from that of ANP32A

Swine ANP32A supports avian influenza virus polymerase

TP Peacock, OC Swann, HA Salvesen… - Journal of …, 2020 - Am Soc Microbiol
Pigs appear uniquely susceptible to both avian and … virus replication, ANP32A, is different
between swine and humans. Swine ANP32A allows a greater range of influenza viruses, …

Mammalian ANP32A and ANP32B proteins drive differential polymerase adaptations in avian influenza virus

TP Peacock, CM Sheppard, MG Lister, E Staller… - Journal of …, 2023 - Am Soc Microbiol
… Incursions of avian influenza viruses into pigs rarely showed … in different avian species
results in a different propensity to … and avian cells lacking pro-viral ANP32 family members has

[HTML][HTML] Mammalian and avian host cell influenza A restriction factors

J McKellar, A Rebendenne, M Wencker, O Moncorgé… - Viruses, 2021 - mdpi.com
… of the high susceptibility of chickens to RNA viruses compared to … In cells from guinea-pigs,
guinea-pig GBP1 has been … in mammalian ANP32A allows avian-origin PB2 to function in …

Mammalian ANP32A and ANP32B proteins drive alternative avian influenza virus polymerase adaptations

TP Peacock, CM Sheppard, E Staller, R Frise… - bioRxiv, 2020 - biorxiv.org
has recently been shown that, although both swine ANP32A … , swine ANP32A has the more
potent pro-viral function and … Incursions of avian influenza viruses into pigs rarely showed …

[HTML][HTML] Selective usage of ANP32 proteins by influenza B virus polymerase: Implications in determination of host range

Z Zhang, H Zhang, L Xu, X Guo, W Wang, Y Ji… - PLoS …, 2020 - journals.plos.org
… evidence of influenza B infection in dogs, guinea pigs, … This suggests that mammals are
more susceptible to IBV … the replication of the avian influenza virus [12, 13]. Chickens have an …

[HTML][HTML] Influenza A virus–host specificity: an ongoing cross-talk between viral and host factors

M Zhang, M Liu, S Bai, C Zhao, Z Li, J Xu… - Frontiers in …, 2021 - frontiersin.org
Avian influenza viruses (AIV) can be divided into low-… thus susceptible to infection of
both human and avian virus, … This unique feature of swine ANP32A was attributed to 106V, …

Role of the viral polymerase during adaptation of influenza A viruses to new hosts

B Gilbertson, M Duncan, K Subbarao - Current Opinion in Virology, 2023 - Elsevier
… animals, including chickens, horses, pigs, and dogs, as well as … Sensitivity or resistance
to BTN3A3 is another factor to … , swine ANP32A is unique among other mammalian ANP32

Avian ANP32A incorporated in avian influenza A virions promotes interspecies transmission by priming early viral replication in mammals

L Na, L Sun, M Yu, Y Zhang, Y Zhang, Z Zhang… - Science …, 2024 - science.org
… and pigs (26, 27). In addition, our recent study provides evidence that ANP32 proteins are
… HiBiT peptide-tagged proteins with high sensitivity when it forms a complex with supplied …

Role of feline ANP32 proteins in regulating polymerase activity of influenza A virus

LU Gang, F ZHENG, Y XIAO, S Ran, J OU… - Journal of Integrative …, 2023 - Elsevier
Avian influenza virus (AIV) isolates generally do not replicate … , pigs, dogs, mice, bats) cell
lines express one single ANP32A … This study provides a new insight into susceptibility of …