… current understanding of C3 glomerulopathy. We present insights relating to the histopathological
diagnosis of C3 glomerulopathy … Genetic and acquired drivers of the disease, potential …

… the two main complement-driven glomerular diseases [5]. C3G is a rare and heterogeneous
… An incomplete recovery of kidney function or the persistence of low serum C3 beyond 8–12 …

… of experts in renal pathology, … C3 glomerulopathy (C3 GP), meeting in Cambridge, UK [2].
Subsequently, new information on the complement system has increased our understanding of …

… C3 glomerulopathy (C3G) is a rare disease resulting from … of complement component 3 (C3)
in the kidney. It encompasses two … was the principal histologic correlate for renal failure [34]. …

… (or Mendelian), complement-driven aHUS and C3-dominant … tested for both aHUS and C3
glomerulopathy (C3G); detailed … thrombocytopenia, and acute kidney failure. The presence of …

… C3 glomerulopathy (C3G) is a rare set of kidney diseases … C3 glomerulonephritis (C3GN)
and dense deposit disease… C3 glomerulopathy (C3G) refers to a group of rare kidney diseases …

… advisor, Richard JH Smith, MD, for entrusting me with our C3 Glomerulopathy patients in …
of the disease to expand our knowledge and ultimately benefit the care of our patients. Thank …

… GN and C3 glomerulopathy are rare and overlapping disorders … Of the patients with C3
glomerulopathy, all 14 patients with an … to kidney failure during the course of this study. All eight …

… many reports consider C3 glomerulopathy as a single disease, in … In rare instances, DDD
may mimic renal vasculitis or present with acute kidney failure or crescentic glomerulonephritis (…

… We review renal diseases in which complement over-activation is known to cause tissue
injury; aHUS and C3 glomerulopathy… C3 glomerulopathy (C3G) is a rare, complement-mediated …