Closed-loop recruitment of striatal interneurons prevents compulsive-like grooming behaviors

SL Mondragón-González, C Schreiweis… - Nature …, 2024 - nature.com
… hyperactivity and a decreased density of PVI in medial striatal areas 6,24,25 . To prove and
… spontaneous compulsive-like self-grooming behaviors, we have established a closed-loop (…

Closed-loop recruitment of striatal parvalbumin interneurons prevents the onset of compulsive behaviours

SL Mondragón-González, C Schreiweis C… - BioRxiv, 2022 - biorxiv.org
striatal PVI recruitment for regulating compulsive-like grooming, we then developed a novel
closed-loop … transient and spontaneous compulsive-like behaviours, we have established a …

[PDF][PDF] Closed-loop recruitment of striatal parvalbumin interneurons prevents the onset of compulsive behaviors

E Burguière - academia.edu
… To investigate further the critical time-window when striatal PVI needed to be recruited for
the behavioural regulation of compulsive-like grooming, we then designed a novel closed-loop

Combining a real-time closed-loop system with neuromodulation: an integrative approach to prevent pathological repetitive behaviors

SLM González - 2019 - theses.hal.science
… -grooming behavior. Through optogenetic stimulation of PVI in the dorsal medial part of the
striatum we were able to effectively prevent … models of compulsive-like behaviors such as the …

Hyperactivity of indirect pathway-projecting spiny projection neurons promotes compulsive behavior

SC Piantadosi, EE Manning, BL Chamberlain… - Nature …, 2024 - nature.com
striatal population activity is better able to classify grooming … We next determined whether
recruitment of functional … technologies allowing automated closed-loop optogenetic stimulation, …

A competitive model for striatal action selection

S Bariselli, WC Fobbs, MC Creed, AV Kravitz - Brain research, 2019 - Elsevier
… In a refined closed-loop stimulation of these pathways, dMSN … striatal pathway alterations
and compulsive-like behavioral … Are different striatal networks recruited and responsible for …

Methylphenidate with or without fluoxetine triggers reinstatement of cocaine seeking behavior in rats

L Lamoureux, J Beverley, H Steiner… - …, 2024 - nature.com
… factors and other signaling molecules in the striatum and shifts the most affected functional …
to prevent exploratory behaviors from interfering with subsequent self-administration behavior

Chemogenetic activation or inhibition of histaminergic neurons bidirectionally modulates recognition memory formation and retrieval in male and female mice

A Costa, E Ducourneau, L Curti, A Masi… - Scientific Reports, 2024 - nature.com
… tasks, which are known to recruit different brain circuitries. To … anxiety- and obsessive–compulsive-like
behaviour s 12 . There … and trials to prevent bias due to place preference. Mice’ …

Dorsal peduncular cortex activity modulates affective behavior and fear extinction in mice

JJ Botterill, A Khlaifia, R Appings, J Wilkin… - …, 2024 - nature.com
… To further characterize the DP/DTT neuronal subpopulations actively recruited during behavior
OFT activating a heterogeneous DP/DTT population containing a minority of interneurons. …

c-Jun N-terminal Kinase (JNK) Regulation of Neuroplastic Changes in Brain Associated with Anxiety-and Depressive-like Behavior

F Marchisella - 2019 - doria.fi
behavior and decrease exploratory behavior preventing effective food search, while in humans
it could affect social behavior … test for anxiety- or compulsive-like behavior. However, as it …