… ERα-caspase7-HDAC3 axis may play a role in promoting the proliferation of endocrine
resistant breast cancer cells. … report that endocrine resistant breast cancer cells with loss of ERα …

… anti-proliferative effect in ER+ breast cancer than ER negative (… revealed a decrease of ERα
expression in LTED cells, when … a HDAC member, HDAC3, as a downstream target of ERα …

… -proliferative, ERα promotes proliferation. Estrogen-activated … Furthermore, inhibition of
HDAC3 was shown to reduce the … This leads to a γ-secretase-dependent cleavage of the Notch …

… Inhibition of HDAC3 has significantly reduced the viability of ERα-deficient … /caspase 7/HDAC3
axis promotes the proliferation of endocrine-resistant BC cells that exhibit ERα loss [72]. …

… that decreasing HDAC3 cleavage in the absence of ERα … proliferation of endocrine-resistant
breast cancer cells, and … endocrine-resistant breast cancers with low ERα expression. …

… Endocrine resistant breast cancer cells with loss of ERα expression retain proliferative
ability by reducing caspase7-mediated HDAC3 cleavage. …

… pathway of cell death induced by anti-cancer drug treatments, … , including cleaved caspase
3 and BAX, while decreasing the anti-… reported role of ERα in improving EGR3 expression, we …

… -induced reduction of HDAC3, we detected the expression of … that breast cancer cells without
ERα expression can keep the … proliferation and increasing apoptosis of breast cancer cells. …

… the pathogenesis of invasive breast cancer, reduced levels of … in ERα positive breast cancer
cells, while TNBC cells showed … the proliferation and motility of breast cancer cells (136–138)…

… inhibition or knockdown using siRNAs led to reduced ERα (… the protein expression levels
of caspase-3, caspase-7, cleaved … We have also examined the extent of cell proliferation by …