[HTML][HTML] Lateral hypothalamus orexinergic inputs to lateral habenula modulate maladaptation after social defeat stress

D Wang, A Li, K Dong, H Li, Y Guo, X Zhang, M Cai… - Neurobiology of …, 2021 - Elsevier
… The orexinergic system is involved in the regulation of multiple motivated behaviors. The …
of orexinergic projections from the lateral hypothalamic area (LHA) to the lateral habenula (LHb…

The basal forebrain to lateral habenula circuitry mediates social behavioral maladaptation

J Wang, Q Yang, X Liu, J Li, YL Wen, Y Hu… - Nature …, 2024 - nature.com
… to the lateral habenula (LHb) was potentiated following social … differential neural activities
and modulation effects in social fear… from the BF to the lateral hypothalamus was linked to food-…

Inhibition within the lateral habenula—Implications for affective disorders

JF Webster, S Lecca, C Wozny - Frontiers in Behavioral Neuroscience, 2021 - frontiersin.org
… BF), the lateral preoptic area and lateral hypothalamus of the … Thus, current evidence
seems to indicate that orexinergic … of bidirectionally modulating excitatory input in different …

Mediation of lateral hypothalamus orexin input to lateral habenula in the inhibitory effects of mechanical stimulation on psychomotor responses induced by cocaine

HB Jang, DB Ahn, HK Kim, X Guan, Y Fan… - Frontiers in Molecular …, 2023 - frontiersin.org
… In vivo extracellular single-unit recordings of lateral hypothalamus (LH) neurons following
… The present study also showed that MS activated LH orexinergic neurons. These results …

[HTML][HTML] Contribution of activating lateral hypothalamus-lateral habenula circuit to nerve trauma-induced neuropathic pain in mice

HW Gu, GF Zhang, PM Liu, WT Pan, YX Tao… - Neurobiology of …, 2023 - Elsevier
… To determine whether LH neurons are activated after … Patients with chronic pain usually
exhibit maladaptive neural … An important finding in this study was that CCI increased the input in …

Multi-level variations of lateral habenula in depression: A comprehensive review of current evidence

GM Zhang, HY Wu, WQ Cui, W Peng - Frontiers in psychiatry, 2022 - frontiersin.org
… to its exceptional location in modulating both the dopaminergic and … The right-side habenula
activation in depression is considerably … Orexinergic lateral hypothalamic area projections …

Chronic social defeat stress induces pathway-specific adaptations at lateral habenula neuronal outputs.

JCH Silva, N Pausic, AM Rivera, B Labonté… - Journal of …, 2024 - jneurosci.org
inputs from many brain regions including the ventral 576 pallidum, the lateral hypothalamus,
… Altogether, we have shown that chronic social stress induced maladaptive changes at 586 …

Response flexibility: The role of the lateral habenula

VI Hones, SJY Mizumori - Frontiers in Behavioral Neuroscience, 2022 - frontiersin.org
… attending to relevant sensory input, determining whether … modulate LHb activity, and
consequently response flexibility. … The lateral hypothalamus (LH) also provides behaviorally-…

Orexin inputs to GABAergic lateral habenula neurons control aggression valence

ME Flanigan - 2019 - search.proquest.com
… of LHb inputs and outputs can function to exert parallel control over reward circuits modulating
the … Glutamatergic inputs to the LHb arise from the lateral hypothalamus (LH), the anterior …

Neural mechanism of acute stress regulation by trace aminergic signalling in the lateral habenula in male mice

SH Yang, E Yang, J Lee, JY Kim, H Yoo… - Nature …, 2023 - nature.com
… whether trace aminergic signalling modulates the effects of … stress activates LHb and lateral
hypothalamus (LH) neurons (… To examine whether the RMTg directly receives synaptic input