… a cysteinyl leukotriene receptor antagonist, exerts local antinociception in animal model of pain through the L-arginine/nitric oxide/cyclic GMP/KATP channel pathway …

E Alizamani, B Ghorbanzadeh… - International Journal …, 2021 - Taylor & Francis
… The leukotrienes are … local montelukast, a cysteinyl leukotriene receptor antagonist, and
the possible involvement of L-arginine/NO/cGMP/K ATP channel pathway and PPARγ receptors

[HTML][HTML] … effect of montelukast, a leukotriene receptor antagonist, on the acetic acid-induced model of colitis in rats: Involvement of NO-cGMP-KATP channels pathway

B Ghorbanzadeh, MA Behmanesh… - Frontiers in …, 2022 - frontiersin.org
Montelukast, a cysteinyl LT receptor antagonist (LTD 4 … Furthermore, we revealed that
montelukast exerts an anti-… Also, montelukast may have anti-inflammatory effects through

The nitric oxide-cyclic GMP-KATP channels pathway contributes to the effects of montelukast against gastric damage induced by ethanol

MA Behmanesh, A Rasekhian, F Kiani… - Alcohol, 2023 - Elsevier
… that ethanol stimulates the LTC 4 generation, cysteinyl LTs, and 15-… of cysteinyl LT receptors,
such as the interaction with the … effect in a local inflammatory pain models in rats (Alizamani …

[HTML][HTML] Leukotriene receptor antagonist, montelukast ameliorates L-Name-induced pre-eclampsia in rats through suppressing the IL-6/Jak2/STAT3 signaling pathway

WY Abdelzaher, G Mostafa-Hedeab, HA Bahaa… - Pharmaceuticals, 2022 - mdpi.com
… Significance: Mont exerted the biochemical and … a selective cysteinyl leukotriene receptor
antagonist, with anti-oxidant, anti-inflammatory, and anti-apoptotic effects in different models of …

[HTML][HTML] Leukotrienes vs. montelukast—activity, metabolism, and toxicity hints for repurposing

CF Marques, MM Marques, GC Justino - Pharmaceuticals, 2022 - mdpi.com
… available but montelukast (MTK)—an antagonist of the cysteinyl … are the cysteinyl leukotriene
receptors 1 (CysLTR 1 ) and 2 (… Local antinociception model of pain Pharmacological …

Analgesic and Anti-inflammatory Effects of Montelukast in Chicks

Y Albadrany, A Naser, YJ Mousa - Egyptian Journal of …, 2024 - ejvs.journals.ekb.eg
… of montelukast is the block of cysteinyl leukotriene (cys-LT) … that antinociception was elicited
in various inflammatory pain … the montelukast inhibit peripheral PPARγ receptors and exert

The role of l-arginine/NO/cGMP/KATP channel pathway in the local antinociceptive effect of berberine in the rat formalin test

M Rahemi, S Mohtadi, HR Vardanjani… - Behavioural …, 2023 - journals.lww.com
… and inhibition of pain transmission by acting on K ATP channels. The current study provides
… a new local antinociceptive agent that can exert its peripheral antinociceptive effect through

Effect of nitric oxidecyclic GMP–K+ channel pathway blockers, naloxone and metformin, on the antinociception induced by the diuretic pamabrom

MI Ortiz, R Cariño-Cortés… - Canadian Journal of …, 2022 - cdnsciencepub.com
… )–K + channel pathway on the local antinociception induced by … of opioid receptors, the
NO–cGMP–K + channels pathway, … , inflammation, and pain. There are four G-protein-coupled …

Role of the NO-cGMP-K+ channels pathway in the peripheral antinociception induced by α-bisabolol

MI Ortiz, R Cariño-Cortés… - Canadian Journal of …, 2021 - cdnsciencepub.com
Montelukast, a cysteinyl leukotriene receptor antagonist, exerts local antinociception in animal
model of pain through the L-arginine/nitric oxide/cyclic GMP/K(ATP) channel pathway and …

[PDF][PDF] Anti-enzymatic and DNA docking studies of montelukast: A multifaceted molecular scaffold with in vitro investigations, molecular expression analysis and …

S Abdullah, A Iqbal, AK Ashok, FC Kaouche, M Aslam… - Heliyon, 2024 - cell.com
… , exerts local antinociception in animal model of pain through the L-arginine/nitric oxide/cyclic
GMP/KATP channel pathway and PPARγ receptors, International Journal …