… of prokaryotic Argonautes (pAgos). pAgos are currently used for in vitro molecular diagnostics
and DNA assembly. There are significant opportunities for in vivo biotechnologies such as …

… , have become research focal points in viral molecular diagnostics. However, CRISPR-Cas …
In vivo, TtAgo forms a complex with small interference DNA (siDNA) guide molecules (13–…

… Here, we describe the role and mechanism of short prokaryotic Argonaute TIR-APAZ (SPARTA…
In vivo, SPARTA is activated in the presence of highly transcribed multicopy plasmid DNA. …

… containing DREN as short prokaryotic Argonaute, DNase and … To test whether SPARDA can
damage DNA in vivo, we … potentially provide programmable tools for biotechnology 54 . As a …

… exogenous genes, or in vivo, where vectors are directly … (pAgos) encode members of the
highly conserved Argonaute … acid editing techniques, molecular diagnostic methods, as …

… from prokaryotic Argonaute proteins (… that prokaryotic Argonaute proteins (pAgos) may
function in the DNA replication and provide cell defense against foreign genetic elements in vivo (5…

… Prokaryotic Argonaute proteins (pAgos) constitute a diverse … that co-purified with CbAgo in
vivo. CbAgo was incubated with … –4 segment that we observed in vivo is also reflected in vitro: …

… and prokaryotic Agos followed in 2013, when it was found that in vivo the catalytically inactive
Argonaute … transcript fragments and short complementary DNA molecules (Olovnikov et al., …

… In vivo, RNA duplexes are formed from tracrRNA and pre-… biosensors capable of using
prokaryotic Argonaute (pAgo) as a … as an emerging class of molecular diagnostics. This paper …

… tracrRNA and pre-crRNA can form an RNA duplex in vivo. After the pre-crRNA in the duplex
is … identified in multiple prokaryotic genomes close to a CRISPR array and adaptation genes. …