Specific T cells targeting Staphylococcus aureus fibronectinbinding protein 1 induce a type 2/type 1 inflammatory response in sensitized atopic dermatitis patients

AK Farag, LM Roesner, S Wieschowski… - Allergy, 2022 - Wiley Online Library
… findings by investigating delayed-type immune reactions, the objective of this study was to
detect and phenotypically characterize FBP1-specific T cells as possible trigger factors in AD. …

The Multivalent Role of Fibronectin-Binding Proteins A and B (FnBPA and FnBPB) of Staphylococcus aureus in Host Infections

P Speziale, G Pietrocola - Frontiers in microbiology, 2020 - frontiersin.org
… and α 5 β 1 integrin on the host cell surface is sufficient to induce zipper-type uptake of …
the target for the staphylococcal infection. Thus, biofilm formation and ability to invade host …

Staphylococcus aureus fibronectin binding protein A mediates biofilm development and infection

CM Gries, T Biddle, JL Bose, T Kielian… - Infection and …, 2020 - Am Soc Microbiol
Staphylococcus aureus is a leading cause of both health care- and community-associated
infections (1)… (Fn), that help modulate a foreign body reaction (6) but also represent a target for …

Surface Proteins of Staphylococcus aureus

TJ Foster - Microbiology spectrum, 2019 - Am Soc Microbiol
… An important exception is the fibronectin binding repeats of fibronectin binding proteins (…
worst case scenario can cause toxic shock syndrome. Depletion of T cells also results in failure …

… invasive Lactobacillus plantarum expressing fibronectin binding protein A induce specific humoral immune response by stimulating differentiation of dendritic cells

J Liu, G Yang, X Gao, Z Zhang, Y Liu… - Beneficial …, 2019 - wageningenacademic.com
… either Staphylococcus aureus fibronectin-binding protein A … that the presence of FnBPA
stimulate the T cells to bias Th2 and … Dendritic cell-targeted recombinantLactobacilli induce DC …

Fibronectin binding protein B binds to loricrin and promotes corneocyte adhesion by Staphylococcus aureus

TM da Costa, A Viljoen, AM Towell, YF Dufrêne… - Nature …, 2022 - nature.com
Staphylococcus aureus is a leading cause of bacterial … This important pathogen can cause
skin and soft tissue infections, … For example, we propose that specifically targeting bacterial …

Staphylococcus aureus Fibronectin-Binding Proteins Contribute to Colonization of the Female Reproductive Tract

LM Lyon, KS Doran, AR Horswill - Infection and Immunity, 2023 - Am Soc Microbiol
… liquid interface Transwell cell culture system to induce vaginal cell differentiation and … cell
culture has been shown to induce polarized cell layer differentiation, form apical anucleate cells

More is not always better—the double-headed role of fibronectin in Staphylococcus aureus host cell invasion

S Niemann, MT Nguyen, JA Eble, AI Chasan… - MBio, 2021 - Am Soc Microbiol
Fibronectin (Fn) was the first adhesive protein implicated in such … Fn binding proteins (FnBP)
A and B on the staphylococcal surface … aureus lipoproteins also have been shown to trigger

Staphylococcus aureus in atopic dermatitis: Strain-specific cell wall proteins and skin immunity

K Iwamoto, M Moriwaki, R Miyake, M Hide - Allergology International, 2019 - jstage.jst.go.jp
T cells was induced by monocyte-derived dendritic cells … to peptidoglycan, such as
fibronectin-binding proteins (FnBPs), … these therapies will target not only skin immunity but also S. …

The Two-Track Investigation of Fibronectin Binding Protein A of Staphylococcus aureus from Bovine Mastitis as a Potential Candidate for Immunodiagnosis: A Pilot …

A Dobrut, A Młodzińska, K Drożdż… - International Journal of …, 2023 - mdpi.com
… [1]. The most common pathogens responsible for mastitis are the bacteria Staphylococcus
aureus… , Escherichia coli, and Klebsiella pneumoniae but fungi and algae cause it as well [4,5]. …