[HTML][HTML] TGF-β induced EMT and stemness characteristics are associated with epigenetic regulation in lung cancer

BN Kim, DH Ahn, N Kang, CD Yeo, YK Kim, KY Lee… - Scientific Reports, 2020 - nature.com
… might be associated with epigenetic regulation in lung cancerTGF-β induced EMT on
stemness acquisition of lung cancerepigenetic mechanisms involved in the development of lung

[HTML][HTML] Aspects of the epigenetic regulation of EMT related to cancer metastasis

E Nowak, I Bednarek - Cells, 2021 - mdpi.com
… in a majority of lung cancer cell lines and primary lung tumors … TGF-β is not only
immunosuppressive but also has EMT … hallmarks of cancer, such as cancer cell stemness, therapy …

EMTassociated microRNAs and their roles in cancer stemness and drug resistance

G Pan, Y Liu, L Shang, F Zhou… - Cancer …, 2021 - Wiley Online Library
EMT-associated miRNAs could inhibit the stemness features in various … that the inhibition
of TGF-β did not suppress EMT in lung cancer cells but induced an EMT-intermediate state, …

[HTML][HTML] Dynamics of phenotypic heterogeneity associated with EMT and stemness during cancer progression

MK Jolly, T Celià-Terrassa - Journal of clinical medicine, 2019 - mdpi.com
… HCC827 lung cancer cells treated with increasing concentrations of TGF-β to induce EMT
(… Connecting these traits of CTC clusters to spatiotemporal dynamics of EMT in a primary …

[HTML][HTML] KDM2B is involved in the epigenetic regulation of TGF-β-induced epithelial–mesenchymal transition in lung and pancreatic cancer cell lines

S Wanna-Udom, M Terashima, K Suphakhong… - Journal of Biological …, 2021 - ASBMB
… in the regulation of TGF-β-induced EMT of A549 lung cancer and Panc1 pancreatic … -related
gene by CRISPR/Cas9 system on the changes in EMT character of A549 lung cancer cell …

[HTML][HTML] TGF-β1 induced deficiency of linc00261 promotes epithelial–mesenchymal-transition and stemness of hepatocellular carcinoma via modulating SMAD3

Z Chen, L Xiang, L Li, H Ou, Y Fang, Y Xu, Q Liu… - Journal of translational …, 2022 - Springer
… in numerous cancers, such as lung cancer [19], gastric cancer [… , a specific TGF-β receptor
(TGF-βR) inhibitor, TGF-β1-inducedEMT and is associated with stem-like traits in HCC cells. …

Chronic TGF-β exposure drives stabilized EMT, tumor stemness, and cancer drug resistance with vulnerability to bitopic mTOR inhibition

Y Katsuno, DS Meyer, Z Zhang, KM Shokat… - Science …, 2019 - science.org
… by TGF-β withdrawal but in which major CSC-associated traits … colonization, assessed by
numbers of lung tumor nodules (… Epigenetic regulation of initiation or maintenance of EMT has …

[HTML][HTML] Epithelial-mesenchymal transition-inducing factors involved in the progression of lung cancers

MW Nam, CW Kim, KC Choi - Biomolecules & Therapeutics, 2022 - ncbi.nlm.nih.gov
… For example, TGF-β induces EMT in lung cancer cells, and … of miR-200 and miR-203
which inhibits stemness. These … in EMT; hence, we have accumulated the characteristics and …

[HTML][HTML] TGF-β, EMT, and resistance to anti-cancer treatment

X Wang, PJA Eichhorn, JP Thiery - Seminars in Cancer Biology, 2023 - Elsevier
… For example, in non-small cell lung cancer (NSCLC), three … chemoresistance, EMT-associated
epigenetic regulations have … of cell stemness and plasticity. Until recently, some studies …

[HTML][HTML] Quantifying cancer epithelial-mesenchymal plasticity and its association with stemness and immune response

D Jia, X Li, F Bocci, S Tripathi, Y Deng, MK Jolly… - Journal of clinical …, 2019 - mdpi.com
… tend to acquire “stemnesscharacteristics, which are … Moreover, TGF-β induced EMT of
mutant cells exhibits … expressed in “mesenchymal” lung adenocarcinoma. Reports also suggest …