[HTML][HTML] Unbiased data mining identifies cell cycle transcripts that predict non-indolent Gleason score 7 prostate cancer

WL Johnston, CN Catton, CJ Swallow - BMC urology, 2019 - Springer
identify SRD5A2, and 11 mitosis and cell cycle transcripts that predict PCa disease progression
in patients with Gleason … 10 of these transcripts extended to patients with Gleason 3 + 4 = …

[HTML][HTML] Random forest-based modelling to detect biomarkers for prostate cancer progression

R Toth, H Schiffmann, C Hube-Magg, F Büscheck… - Clinical …, 2019 - Springer
… of DNA methylation linked to mitotic cell division. We selected several … ZIC2 belongs to a
family of transcription factors involved in … From 2005 on, in our department, Gleason grading was …

Decoding The Evolutionary Response To Prostate Cancer Therapy Using Plasma Genome Sequencing

N Ramesh - 2020 - digitalcommons.library.tmc.edu
predict when cancer and treatment response. If the patients have an elevated PSA, biopsies
are taken to grade the tumor using the Gleason … Our unbiased analysis also identified CNAs …

Prostate cancer genomic subtypes

M Fraser, A Rouette - Prostate Cancer: Cellular and Genetic Mechanisms …, 2019 - Springer
… androgen-driven transcription. While chromoplexy has been … S/G2 phases of the cell cycle.
In addition to germline variants, … Gleason upgrade at prostatectomy), comparatively little data

Evaluating novel prognostic biomarkers in prostate cancer

BS Simpson - 2022 - discovery.ucl.ac.uk
… -regulated in PCa cell lines (LNCaP) and enriched in high Gleason grade PCa tissue …
follow-up data. Within these cohorts, SYBU mRNA expression independently predicted outcomes …

[HTML][HTML] Novel gene signatures predictive of patient recurrence-free survival and castration resistance in prostate cancer

B Zhang, Z Zhang, H Hu, JT Dong - Cancers, 2021 - mdpi.com
… , including tumors with the Gleason score of seven and those … We identified 287 differentially
expressed genes (DEGs) … , the processes of cell cycle progression, stem cell division, and …

[HTML][HTML] The Prognostic Value of Liquid Biopsies for Benefit of Salvage Radiotherapy in Relapsed Oligometastatic Prostate Cancer

NV Bogdanova, H Radmanesh, D Ramachandran… - Cancers, 2022 - mdpi.com
… , the Gleason score, and tumor categories for predicting RT … Identifying differentially expressed
transcripts stratified by the … transcripts built a “transcriptional signature” for the Gleason

[HTML][HTML] Genetic landscape of prostate cancer conspicuity on multiparametric magnetic resonance imaging: a systematic review and bioinformatic analysis

JM Norris, BS Simpson, MA Parry, C Allen… - European Urology Open …, 2020 - Elsevier
… We also identify genes associated with mpMRI conspicuity, … Pathways that regulate cell
cycle and growth appear to be … that were predicted did not significantly differ by Gleason grade, …

[HTML][HTML] The miR-96 and RARγ signaling axis governs androgen signaling and prostate cancer progression

MD Long, PK Singh, JR Russell, G Llimos, S Rosario… - Oncogene, 2019 - nature.com
… We also reasoned that higher Gleason grade tumors were … of selected cell cycle regulators
and transcription factors (eg, … De-identified patient codes were matched with Gleason

A nomogram based on a gene signature for predicting the prognosis of patients with head and neck squamous cell carcinoma

B Yang, L Fu, S Xu, J Xiao, Z Li… - The International Journal …, 2019 - journals.sagepub.com
… In this study, we identified seven genes that predict the OS of … apart from speedy/RINGO cell
cycle regulator family member C (… , and lower SRD5A2 transcript abundance has previously …