[HTML][HTML] Nrf2/Wnt resilience orchestrates rejuvenation of glia-neuron dialogue in Parkinson's disease

B Marchetti - Redox biology, 2020 - Elsevier
… Here, the cellular and molecular aspects as well as the therapeutical options for rejuvenating
glia-neuron dialogue will be discussed together with major glial-derived mechanisms and …

Neuroprotective benefits of grape seed and skin extract in a mouse model of Parkinson's disease

S Ben Youssef, G Brisson… - Nutritional …, 2021 - Taylor & Francis
protected against neuronal loss and improved motor function in an in vivo 6-OHDA model of
Parkinson’s disease (PD)… to protect dopamine neurons from degeneration in a model of PD. …

The neuroprotective effects and transdifferentiation of astrocytes into dopaminergic neurons of Ginkgolide K on Parkinson'disease mice

Q Miao, Z Chai, LJ Song, Q Wang, GB Song… - Journal of …, 2022 - Elsevier
… of GK for protecting TH + neurons by multiple and … neurons in the MPTP mouse model
of PD, and is the vital player in the development and neurogenesis of dopaminergic neurons (…

Treating Parkinson's disease by astrocyte reprogramming: Progress and challenges

ZYD Wei, AK Shetty - Science Advances, 2021 - science.org
… midbrain astrocytes into functional DA-ergic neurons in a mouse model of PD is an exciting
… the lost DA-ergic neurons in PD. Since this study was performed in a mouse model of PD, it …

Umbilical cord blood-derived exosomes attenuate dopaminergic neuron damage of Parkinson's disease mouse model

J Ye, X Sun, Q Jiang, J Gui, S Feng, B Qin, L Xie… - Journal of …, 2024 - Springer
… PD mice model To further investigate how UCB-Exos treatment protects dopaminergic neurons,
… nigra to detect the number of dopaminergic neurons and the activation of glial cells. We …

[HTML][HTML] Neural regeneration therapies for Alzheimer's and Parkinson's disease-related disorders

AP Reddy, J Ravichandran, N Carkaci-Salli - … )-Molecular Basis of Disease, 2020 - Elsevier
… AD and PD mouse models and 2) regenerative medicine in AD and PD mouse models, and
… and can protect neurons from Aβ species, uncoupling tau protein, and oxidative stress [131]. …

Boosting antioxidant self-defenses by grafting astrocytes rejuvenates the aged microenvironment and mitigates nigrostriatal toxicity in Parkinsonian brain via an Nrf2 …

MF Serapide, F L'Episcopo, C Tirolo, N Testa… - Frontiers in Aging …, 2020 - frontiersin.org
… are being pursued to develop novel therapeutic regimens for PD, including cell therapies,
aimed at protecting or enhancing the intrinsic regenerative potential of DAergic neurons. …

[HTML][HTML] MPTP-induced mouse model of Parkinson's disease: A promising direction for therapeutic strategies

M Mustapha, CNM Taib - Bosnian journal of basic medical …, 2021 - ncbi.nlm.nih.gov
… The model has rejuvenated PD research and opened new frontiers in the quest for more
novel therapeutic and adjuvant agents for PD. Hence, this review summarizes the role of MPTP …

From regenerative strategies to pharmacological approaches: can we fine-tune treatment for Parkinson's disease?

RC Silva, HS Domingues, AJ Salgado… - Neural Regeneration …, 2022 - journals.lww.com
… for Parkinson's disease, given its ability to modulate cell viability/preservation of dopaminergic
neurons. … -modifying therapies for PD could be approached globally with a rejuvenating

Apelin-36 mediates neuroprotective effects by regulating oxidative stress, autophagy and apoptosis in MPTP-induced Parkinson's disease model mice

J Zhu, W Gao, X Shan, C Wang, H Wang, Z Shao… - Brain research, 2020 - Elsevier
… And our recent works have demonstrated that intranigral injection of Apelin-13 protected
dopaminergic neurons in MPTP-treated PD mice model through promoting autophagy and …