[HTML][HTML] Nrf2/Wnt resilience orchestrates rejuvenation of glia-neuron dialogue in Parkinson's disease
B Marchetti - Redox biology, 2020 - Elsevier
… Here, the cellular and molecular aspects as well as the therapeutical options for rejuvenating
glia-neuron dialogue will be discussed together with major glial-derived mechanisms and …
glia-neuron dialogue will be discussed together with major glial-derived mechanisms and …
Neuroprotective benefits of grape seed and skin extract in a mouse model of Parkinson's disease
S Ben Youssef, G Brisson… - Nutritional …, 2021 - Taylor & Francis
… protected against neuronal loss and improved motor function in an in vivo 6-OHDA model of
Parkinson’s disease (PD)… to protect dopamine neurons from degeneration in a model of PD. …
Parkinson’s disease (PD)… to protect dopamine neurons from degeneration in a model of PD. …
The neuroprotective effects and transdifferentiation of astrocytes into dopaminergic neurons of Ginkgolide K on Parkinson'disease mice
Q Miao, Z Chai, LJ Song, Q Wang, GB Song… - Journal of …, 2022 - Elsevier
… of GK for protecting TH + neurons by multiple and … neurons in the MPTP mouse model
of PD, and is the vital player in the development and neurogenesis of dopaminergic neurons (…
of PD, and is the vital player in the development and neurogenesis of dopaminergic neurons (…
Treating Parkinson's disease by astrocyte reprogramming: Progress and challenges
… midbrain astrocytes into functional DA-ergic neurons in a mouse model of PD is an exciting
… the lost DA-ergic neurons in PD. Since this study was performed in a mouse model of PD, it …
… the lost DA-ergic neurons in PD. Since this study was performed in a mouse model of PD, it …
Umbilical cord blood-derived exosomes attenuate dopaminergic neuron damage of Parkinson's disease mouse model
J Ye, X Sun, Q Jiang, J Gui, S Feng, B Qin, L Xie… - Journal of …, 2024 - Springer
… PD mice model To further investigate how UCB-Exos treatment protects dopaminergic neurons,
… nigra to detect the number of dopaminergic neurons and the activation of glial cells. We …
… nigra to detect the number of dopaminergic neurons and the activation of glial cells. We …
[HTML][HTML] Neural regeneration therapies for Alzheimer's and Parkinson's disease-related disorders
AP Reddy, J Ravichandran, N Carkaci-Salli - … )-Molecular Basis of Disease, 2020 - Elsevier
… AD and PD mouse models and 2) regenerative medicine in AD and PD mouse models, and
… and can protect neurons from Aβ species, uncoupling tau protein, and oxidative stress [131]. …
… and can protect neurons from Aβ species, uncoupling tau protein, and oxidative stress [131]. …
Boosting antioxidant self-defenses by grafting astrocytes rejuvenates the aged microenvironment and mitigates nigrostriatal toxicity in Parkinsonian brain via an Nrf2 …
MF Serapide, F L'Episcopo, C Tirolo, N Testa… - Frontiers in Aging …, 2020 - frontiersin.org
… are being pursued to develop novel therapeutic regimens for PD, including cell therapies,
aimed at protecting or enhancing the intrinsic regenerative potential of DAergic neurons. …
aimed at protecting or enhancing the intrinsic regenerative potential of DAergic neurons. …
[HTML][HTML] MPTP-induced mouse model of Parkinson's disease: A promising direction for therapeutic strategies
M Mustapha, CNM Taib - Bosnian journal of basic medical …, 2021 - ncbi.nlm.nih.gov
… The model has rejuvenated PD research and opened new frontiers in the quest for more
novel therapeutic and adjuvant agents for PD. Hence, this review summarizes the role of MPTP …
novel therapeutic and adjuvant agents for PD. Hence, this review summarizes the role of MPTP …
From regenerative strategies to pharmacological approaches: can we fine-tune treatment for Parkinson's disease?
RC Silva, HS Domingues, AJ Salgado… - Neural Regeneration …, 2022 - journals.lww.com
… for Parkinson's disease, given its ability to modulate cell viability/preservation of dopaminergic
neurons. … -modifying therapies for PD could be approached globally with a rejuvenating …
neurons. … -modifying therapies for PD could be approached globally with a rejuvenating …
Apelin-36 mediates neuroprotective effects by regulating oxidative stress, autophagy and apoptosis in MPTP-induced Parkinson's disease model mice
J Zhu, W Gao, X Shan, C Wang, H Wang, Z Shao… - Brain research, 2020 - Elsevier
… And our recent works have demonstrated that intranigral injection of Apelin-13 protected
dopaminergic neurons in MPTP-treated PD mice model through promoting autophagy and …
dopaminergic neurons in MPTP-treated PD mice model through promoting autophagy and …