[HTML][HTML] Antihypertensive effects of whey protein hydrolysate involve reshaping the gut microbiome in spontaneously hypertension rats

P Dou, X Li, X Zou, K Wang, L Yao, Z Sun… - Food Science and …, 2024 - Elsevier
… by increased systemic arterial blood pressure, has become … , causing left ventricle hypertrophy
and diastolic dysfunction, … captopril has rapid and significant antihypertensive effects in …

Identification of celastrol as a novel therapeutic agent for pulmonary arterial hypertension and right ventricular failure through suppression of Bsg (Basigin)/CyPA …

R Kurosawa, K Satoh, T Nakata, T Shindo… - … , and Vascular …, 2021 - Am Heart Assoc
… cardiac fibrosis and failure in the left ventricle in response to … Also, Bsg is an essential
receptor for CyPA (cyclophilin A) that … To evaluate the effect of celastrol on RV itself, we treated …

Systolic dysfunction of systemic ventricle in patients who underwent a Fontan operation

T Öner, Ş Ballı, EH Yılmaz, MO Bulut… - The Turkish Journal …, 2019 - turkjpediatr.org
… atresia and 74 (40.4%) had pulmonary hypertension. The most … had a left ventricular
structure of the systemic ventricle, 14 … synchronization is necessary for optimal Fontan function. …

Curcumin Nanoemulsion: Unveiling Cardioprotective Effects via ACE Inhibition and Antioxidant Properties in Hypertensive Rats

M Ishaq, MF Khan, G Verma, A Rathi, M Adil, M Faizan… - Medicina, 2023 - mdpi.com
… of established standard drugs: captopril and pure curcumin in an … for assessing arterial blood
pressure and heart rate with a … up to the left ventricle to record left ventricular pressure (LVP)…

Angiotensin Regulation of Vascular Homeostasis: Exploring the Role of ROS and RAS Blockers

N Koumallos, E Sigala, T Milas, NG Baikoussis… - International Journal of …, 2023 - mdpi.com
… such as left ventricular hypertrophy, systolic dysfunction, heart failure, … are essential primary
therapies for high blood pressure, … The beneficial effects of captopril were associated with the …

Pharmacological anti-remodelling effects of disease-modifying drugs in heart failure with reduced ejection fraction

M Correale, P Mazzeo, L Tricarico, F Croella… - Clinical Drug …, 2022 - Springer
… an acceptable forward flow from the left ventricle [6]. Major … trend on ventricular remodelling
[45]: after 48 weeks, both captopril and … Mineralocorticoid hormones exert essential effects on …

Computational Insights into Captopril's Inhibitory Potential Against MMP9 and LCN2 in Bladder Cancer: Implications for Therapeutic Application

SK Annana, J Ferdoush, F Lamia, A Roy… - Cancer …, 2024 - journals.sagepub.com
Captopril is commonly used in the treatment of renovascular hypertension, congestive heart
failure, left ventricular … play a crucial role in BLCA. Remarkably, our results indicate that …

Characterization of ACE inhibitory peptide from Cassia tora L. globulin fraction and its antihypertensive activity in SHR

P Chen, Y Ren, Y Zhang, Y Liu, H Shi, Z Chen… - … Food Research and …, 2022 - Springer
left ventricle remodeling was prevented in the TTPSY group. Captopril showed cardio-improvement
effects … , which obviously decreased mean arterial blood pressure, was detected in …

Fibroblasts under pressure: cardiac fibroblast responses to hypertension and antihypertensive therapies

U Chalise, TM Hale - American Journal of Physiology-Heart …, 2024 - journals.physiology.org
… 90 fibroblasts in the left ventricle of hypertensive rats both before … within the hypertensive
left 355 ventricle will be crucial in … to the antifibrotic effect of 949 captopril by accelerating the …

The protective effects of liguzinediol on congestive heart failure induced by myocardial infarction and its relative mechanism

Q Chen, D Zhang, Y Bi, W Zhang, Y Zhang, Q Meng… - Chinese Medicine, 2020 - Springer
left ventricular contractility and improve the diastolic function … )/Smads pathway plays an
essential role in the pathogenesis … Captopril, Digoxin, and liguzinediol could inhibit the declines …